Object:
This study aimed to assess the relationships between trend of mortality rate from subarachnoid hemorrhage (SAH) and blood pressure and smoking prevalence among about 700,000 residents of Shimane prefecture, Japan.
Methods:
A retrospective review was performed to identify the age-adjusted mortality rate from SAH calculated using the standard population of Japan in 2010 and changes in population of Shimane prefecture used the date based on government statistics during 1999 through 2017. Blood pressure dates were extracted from Ministry of Health, Labour and Welfare during 2008 through 2015, and smoking prevalence from Cancer Registry and Statistics. Cancer Information Service, National Cancer Center, Japan every 3 years since 2001.
Result:
Age-adjusted mortality rate from SAH in Shimane prefecture tended to decline by 3.6% between 1999 through 2017 regardless of gender, as 14.86 (95%CI:14.65-15.07) per 100,000 person-year in 1999 to 7.96 (95%CI:7.81-8.11) in 2017. The Population of Shimane prefecture, where one of the most aging region in Japan, was decreased by 10.4% since 764,291 in 1999 to 684,668 in 2017. Blood pressure was invariable during 2008 through 2015, while smoking prevalence decreased since 2001 to 2016, as 25.0% to 18.0%.
Conclusion:
Age-adjusted mortality rate from SAH in Shimane prefecture have declined since 1999 to 2017, regardless of decrease of population and advancement of aging region. The factor of decline might be not only development of treatment and management, but decrease of incidence of SAH in Japan accompanied by improvement of smoking prevalence or lifestyle habitation.
Discussions of Cancer Clinical Trials with the National Cancer Institute's Cancer Information Service
