Olopatadine hydrochloride ophthalmic solution for the treatment of allergic conjunctivitis

2017 ◽  
Vol 18 (11) ◽  
pp. 1137-1143 ◽  
Author(s):  
Alexei Gonzalez-Estrada ◽  
Keerthi Reddy ◽  
Ves Dimov ◽  
Frank Eidelman
Keyword(s):  
Allergic Conjunctivitis ◽  
Ophthalmic Solution ◽  
Olopatadine Hydrochloride

scholarly journals A study on the Therapeutic Efficacy of Olopatadine Hydrochloride in the Management of Allergic Conjunctivitis

1970 ◽  
Vol 22 (1) ◽  
pp. 15-19
Author(s):  
Md Abu Nayeem Chowdhury ◽  
AKM Mosharrof Hossain ◽  
MA Hashem Chowdhury ◽  
Shakhawat Hossain Chowdhury
Keyword(s):  
Allergic Conjunctivitis ◽  
Ophthalmic Solution ◽  
Signs And Symptoms ◽  
College Hospital ◽  
Medical College ◽  
Department Of Ophthalmology ◽  
Drug Adverse Effects ◽  
The Mean ◽  
Medicine Today ◽  
Olopatadine Hydrochloride

A prospective interventional study was conducted to see the efficacy and safety of a ophthalmic preparation olopatadine hydrochloride (0.1%) on 40 allergic conjunctivitis patients attended the out-patient department of Ophthalmology, Sylhet M.A.G. Osmani Medical College Hospital. One drop of ophthalmic solution was administered 12 hourly in each eye for 2 weeks. Scoring of hyperaemia, itching, tearing, and photophobia were estimated before and 2 weeks after administration of the drug. After 30 min. & 2 weeks of administration of drug adverse effects were assessed if there was any. The mean scores of hyperaemia, tearing, itching and photophobia were reduced after 2 weeks of treatment. The scores of hyperaemia, itching, tearing, photophobia were found to be lower compared to Day 0. This change was statistically significant (p < 0.001). Olopatadine appeared to reduce ocular signs and symptoms in Allergic conjunctivitis . Key words: Olopatadine hydrochloride; Allergic conjunctivitis; Hyperaemia; Tearing; Itching; Photophobia. DOI: 10.3329/medtoday.v22i1.5599 Medicine Today Vol.22(1) 2010. 15-19

scholarly journals A comparison of the efficacy of Olopatadine hydrochloride 0.1% ophthalmic solution and Sodium Chromoglycate ophthalmic solution in the treatment of allergic conjunctivitis

1970 ◽  
Vol 18 (2) ◽  
pp. 136-139
Author(s):  
AIMA Uddin ◽  
GM Faruque ◽  
AQMO Sharif
Keyword(s):  
Allergic Conjunctivitis ◽  
Ophthalmic Solution ◽  
Eye Drops ◽  
Blinded Study ◽  
Group A ◽  
The Difference ◽  
Group B ◽  
Double Blinded ◽  
Symptoms And Signs ◽  
Olopatadine Hydrochloride

Aim: To find out an effective drug for the treatment of allergic conjunctivitis and to compare the efficacy of Sodium chromoglycate ophthalmic solution and Olopatadine Hydrochloride 0.1% ophthalmic solution in the treatment of allergic conjunctivitis. Materials and methods: This randomized double blinded study was conducted in National Institute of Ophthalmology and Hospital, Sher-E-BangIa Nagar, Dhaka, from January, 2005 to May, 2009. 100 Patients with ocular allergies attending OPD of NIO&H were included. Each of the patient was randomly included in either of the following two groups by simple lottery method; Group A: 50 Patients receiving olopatadine hydrochloride 0.1% eye drops and Group B: 50 Patients receiving sodium chromoglycate 2% eye drops. Itching score, Redness score, Discharge score, Evaluator's score - baseline and after 21 days of treatment with olopatadine and sodium chromoglycate 2% ophthalmic solution were evaluated following Aguilar (2000). For the relieving of symptoms and signs olopatadine was found to be superior over sodium chromoglycate 2% but the difference was not statistically significant. Conclusion: This clinical study concludes that the relieving of symptoms and signs olopatadine was found to be superior over sodium chromoglycate 2% but the difference was not statistically significant. DOI: 10.3329/jdmc.v18i2.6274 J Dhaka Med Coll. 2009; 18(2) : 136-139

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