Palliative radiation in advanced cancer patients with symptomatic bone metastases

2016 ◽  
Vol 1 (6) ◽  
pp. 449-457
Author(s):  
Sarah Baker ◽  
Alysa Fairchild
2013 ◽  
Vol 21 (11) ◽  
pp. 3021-3030 ◽  
Author(s):  
Kinsey Lam ◽  
Edward Chow ◽  
Liying Zhang ◽  
Erin Wong ◽  
Gillian Bedard ◽  
...  

2015 ◽  
Vol 33 (29_suppl) ◽  
pp. 110-110
Author(s):  
Sanders Chang ◽  
Cardinale B. Smith ◽  
R. Sean Morrison ◽  
Kenneth Rosenzweig ◽  
Kavita Vyas Dharmarajan

110 Background: Single-fraction and ≤ 5 fraction radiation treatment (SF-RT and Hypo-RT, respectively) is underutilized despite strong evidence regarding its efficacy in symptom management. Established in 2013, the Palliative Radiation Oncology Consult Service (PROC) is a specialty service designed to provide individualized, efficient treatment for advanced cancer patients by a radiation oncology team with a dedicated palliative care focus. We assessed the impact of this new model of care on use of SF-RT, hypo-RT, pain improvement, palliative care utilization, and hospitalization among patients treated with palliative radiation (PRT) for painful bone metastases. Methods: We searched electronic charts of advanced cancer patients who had PRT for symptomatic bone mets from Dec 2010 to April 2015, extracting PRT details, demographics, cancer type, pain pre- and 1 month post-PRT, comorbidities (summarized using Charlson comorbidity index [CCI]), palliative care consults, and hospitalization. Comparisons were made before and after PROC using chi-square or t-tests. Multivariable logistic regression estimated the likelihood of SF-RT or hypo-RT, controlling for age, gender, cancer type, treatment site, and CCI. Results: We identified 334 patients, described in the table below. Patients were more likely to have SF-RT (OR 2.2, 95% CI [1.2-3.8], p = 0.007), or hypo-RT (OR 3.0, 95% CI [1.8-4.7], p < 0.001) after establishment of PROC. Conclusions: Establishment of a PROC service nearly doubled utilization of SF-RT and hypo-RT while maintaining pain improvement, and was associated with an increased use of palliative care consult services, decreased inpatient PRT use, and decreased length of stay. A dedicated service combining palliative care principles and radiation oncology improved quality of palliative cancer care. [Table: see text]


1994 ◽  
Vol 10 (1) ◽  
pp. 10-13 ◽  
Author(s):  
Hideo Yoshioka ◽  
Satoru Tsuneto ◽  
Tetsuo Kashiwagi

Morphine was administered to 56 advanced cancer patients; of that number spinal metastases had induced bone pain in 28 and malignant tumors had induced sciatica in 28. The sciatica was caused in 16 patients by direct invasion of the sacral plexus, in four by lumbar bone metastases, and in eight by pelvic bone metastases. Spinal bone pain was controlled adequately with morphine. However, sciatica required larger dosages of morphine than did bone pain. Among the group with sciatica, rectal cancer patients needed larger dosages of morphine than the other cancer patients. Even with high doses of morphine, it was occasionally difficult to control neuropathic pain of the sciatic nerve caused by intrapelvic cancer.


2018 ◽  
Vol 21 (4) ◽  
pp. 438-444 ◽  
Author(s):  
Sanders Chang ◽  
Peter May ◽  
Nathan E. Goldstein ◽  
Juan Wisnivesky ◽  
Kenneth Rosenzweig ◽  
...  

2014 ◽  
Vol 22 (7) ◽  
pp. 1765-1771 ◽  
Author(s):  
Breanne Lechner ◽  
Carlo DeAngelis ◽  
Noreen Jamal ◽  
Urban Emmenegger ◽  
Natalie Pulenzas ◽  
...  

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