Measurement of hand bone mineral content using single-photon absorptiometry

1987 ◽  
Vol 32 (6) ◽  
pp. 697-706 ◽  
Author(s):  
J J Nicoll ◽  
M A Smith ◽  
D Reid ◽  
E Law ◽  
N Brown ◽  
...  
1991 ◽  
Vol 11 (6) ◽  
pp. 620-624 ◽  
Author(s):  
Mahmoud El-Desouki ◽  
Abdulrahman Al-Nuaim ◽  
Mayson N. Al-Mutib ◽  
Riad A. Sulimani ◽  
Hassin Abu-Aisha ◽  
...  

1990 ◽  
Vol 123 (1) ◽  
pp. 14-18 ◽  
Author(s):  
H. Resch ◽  
P. Pietschmann ◽  
E. Krexner ◽  
W. Woloszczuk ◽  
R. Willvonseder

Abstract. A double-blind, placebo-controlled study on 31 patients with osteoporotic spine fractures was performed in order to assess the effects of one-year cyclical estrogen/gestagen replacement therapy (Trisequens, Novo) on peripheral bone mineral content and bone turnover. Bone mineral content was measured by single-photon absorptiometry with 125I before, and 6 and 12 months after start of therapy. Calcium, phosphate, alkaline phosphatase, parathyroid hormone, calcidiol, calcitonin and 2-hour urinary hydroxyproline excretion were measured to evaluate bone turnover. After 12 months, forearm bone mineral content showed a significant increase (p<0.02) in the treatment group, whereas in the control group no statistically significant change in peripheral bone mass was observed. Parameters of bone metabolism showed a decrease in hydroxyproline excretion (p<0.02) as well as alkaline phosphatase (p<0.01) and no changes in parathyroid hormone, calcidiol, and calcitonin. These results demonstrate that one-year cyclical estrogen/gestagen replacement therapy improves peripheral bone mineral content measured by single-photon absorptiometry. This effect appears to be induced by an inhibition of bone resorption.


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