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Artificial intelligence (AI)-driven voice technology deployed on mobile phones and smart speakers has a potential to improve patient management and organizational workflow. Voice chatbots have been already implemented in healthcare leveraging innovative telehealth solutions towards coronavirus emergency and routine clinical work allowing for automatic acute care triage and chronic disease management including remote monitoring, preventive care, patient intake and referral assistance. The article focuses on the current clinical needs and applications of medical-grade voice AI chatbots to drive operational effectiveness, improve patient experience and outcomes.