Construction and Characterization of a Partial Library of Yeast Artificial Chromosomes from Human Chromosome 21

1991 ◽  
Vol 10 (4) ◽  
pp. 301-310 ◽  
Author(s):  
M. BELLIS ◽  
A. GÉRARD ◽  
J.P. CHARLIEU ◽  
B. MARÇAIS ◽  
M.E. BRUN ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Chromosome 21 ◽  
Artificial Chromosomes ◽  
Human Chromosome 21 ◽  
Yeast Artificial Chromosomes

scholarly journals Construction of human chromosome 21-specific yeast artificial chromosomes.

1989 ◽  
Vol 86 (24) ◽  
pp. 9991-9995 ◽  
Author(s):  
M. K. McCormick ◽  
J. H. Shero ◽  
M. C. Cheung ◽  
Y. W. Kan ◽  
P. A. Hieter ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Chromosome 21 ◽  
Artificial Chromosomes ◽  
Human Chromosome 21 ◽  
Yeast Artificial Chromosomes

Cloning and Characterization of a 135- to 500-kb Region of Homology on the Long Arm of Human Chromosome 21

Genomics ◽  
1994 ◽  
Vol 22 (2) ◽  
pp. 472-477 ◽  
Author(s):  
A. Dutriaux ◽  
J. Rossier ◽  
W. Van Hul ◽  
D. Nizetic ◽  
D. Theophille ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Chromosome 21 ◽  
Human Chromosome 21

Cloning and Characterization of EagI YACs from Human Chromosome 21

Genomics ◽  
1993 ◽  
Vol 15 (1) ◽  
pp. 228-230 ◽  
Author(s):  
Jeffrey C. Gingrich ◽  
Stephen R. Lowry ◽  
Wen-Lin Kuo ◽  
Joe Gray ◽  
Cassandra L. Smith ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Chromosome 21 ◽  
Human Chromosome 21

Characterization of yeast artificial chromosomes containing interleukin genes on human chromosome 5

1992 ◽  
Vol 61 (4) ◽  
pp. 263-265 ◽  
Author(s):  
W. Stock ◽  
S.C. Chandrasekharappa ◽  
W.L. Neuman ◽  
M.M. LeBeau ◽  
B.H. Brownstein ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Chromosome 5 ◽  
Artificial Chromosomes ◽  
Yeast Artificial Chromosomes ◽  
Human Chromosome 5

Isolation and Characterization of 14 CA-Repeat Microsatellites from Human Chromosome 21

Genomics ◽  
1993 ◽  
Vol 18 (1) ◽  
pp. 151-155 ◽  
Author(s):  
A. Bosch ◽  
V. Nunes ◽  
D. Patterson ◽  
X. Estivill
Keyword(s):  
Human Chromosome ◽  
Chromosome 21 ◽  
Ca Repeat ◽  
Human Chromosome 21 ◽  
Isolation And Characterization

scholarly journals Establishment of Sequence-Tagged Sites on 15q11-q13 byAlu-Vector PCR Cloning of Yac-Generated Fragments

1996 ◽  
Vol 12 (4) ◽  
pp. 241-246
Author(s):  
W. S. Kim ◽  
Z. M. Deng ◽  
N. T. Nassif ◽  
A. Smith ◽  
R. J. Trent
Keyword(s):  
Human Chromosome ◽  
Angelman Syndrome ◽  
Chromosome 15 ◽  
Loss Of Function ◽  
Pcr Cloning ◽  
Artificial Chromosomes ◽  
Sequence Tagged Sites ◽  
Pcr Products ◽  
Yeast Artificial Chromosomes

Angelman syndrome (AS) is caused by the loss of function of undefined gene(s) on human chromosome 15. The majority of subjects have deletions involving maternally-derived chromosome 15q II-q 13, and the shortest region of deletion overlap (SRO) has been localized to the region between D15S10 and D15S113. In this study, yeast artificial chromosomes (YACs), 6G-D4, 9H-D2 and 37D-F9, mapping within the AS SRO, were isolated from the ICI Y AC library.Alu-vector PCR products were amplified from the YACs and from YACs A229A2 and A33FI 0 which had been obtained from the St. Louis Y AC library. The PCR products were cloned and sequenced, and three new sequence-tagged sites were generated within the AS SRO, facilitating the characterization of gene(s) involved in the Angelman syndrome.

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