Prenatal Genetic Counseling Issues in Women of Advanced Reproductive Age

1993 ◽  
Vol 2 (1) ◽  
pp. 1-5 ◽  
Author(s):  
OWEN P. PHILLIPS ◽  
SHERMAN ELIAS
2006 ◽  
Vol 25 (3) ◽  
pp. 193-219 ◽  
Author(s):  
LINDA M. HUNT ◽  
HEIDE CASTAÑEDA ◽  
KATHERINE B. DE VOOGD

2017 ◽  
Vol 39 (8) ◽  
pp. 685-695 ◽  
Author(s):  
Kimberly E. Liu ◽  
Allison Case

Author(s):  
Neha V. Harne ◽  
Vaibhav K. Nadkarni ◽  
Purnima Nadkarni ◽  
Jigna Garasia

Female fertility begins to decline many years prior to the onset of menopause despite continued regular ovulatory cycles. Although there is no strict definition of advanced reproductive age in women, infertility becomes more pronounced after the age of 35. In the female, the number of oocytes decreases with age until the menopause. Oocyte quality also diminishes, due in part to increased aneuploidy because of factors such as changes in spindle integrity. Although older male age affects the likelihood of conception, abnormalities in sperm chromosomes and in some components of the semen analysis are less important than the frequency of intercourse. Age is as accurate as any other predictor of conception with assisted reproductive technology.


2020 ◽  
Vol 37 (10) ◽  
pp. 2443-2451
Author(s):  
K. Lattes ◽  
S. López ◽  
M. A. Checa ◽  
M. Brassesco ◽  
D. García ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document