scholarly journals Is the routine use of trimodality therapy for selected patients with non-small cell lung cancer supported by long-term clinical outcomes?

2017 ◽  
Vol 28 (1) ◽  
pp. 185 ◽  
Author(s):  
C. Dickhoff ◽  
K.J. Hartemink ◽  
J. Kooij ◽  
P.M. van de Ven ◽  
M.A. Paul ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Clinical Outcomes ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Trimodality Therapy

Cytogenetic Findings in Primary Non-Small Cell Lung Cancer

1994 ◽  
Vol 80 (2) ◽  
pp. 151-156
Author(s):  
Elvira D'Alessandro ◽  
Maria Luisa Lo Re ◽  
Roberto Crisci ◽  
Claudio Ligas ◽  
Giorgio Furio Coloni
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Chromosome Loss ◽  
Small Cell Lung ◽  
Primary Nsclc ◽  
Cytogenetic Analyses ◽  
Triploid Clone

Non-small cell lung cancer (NSCLC) shows a complex cytogenetic heterogeneity and up to now no particular chromosomal aberration seems to characterize its malignant evolution. We therefore performed cytogenetic analyses of 20 primary NSCLC, 8 adenocarcinomas and 12 squamous cell carcinomas on direct preparations or short-term cultures. Only 1 case was analyzed after long-term culture. Results were obtained from 11 samples and clonal rearrangements were found in 3 cases, a diploid and a near-triploid clone with several aberrations such as i (9q), rob (14; 15) and rob (21; 21) in 1 case, a near-triploid clone in 1 case, and Y chromosome loss in 1 case. Other aberrations found were sporadic, but + 7 aneuploidy and translocations involving 1p were detected in 2 and 3 samples respectively. Although to date it has been very difficult to recognize primary changes in NSCLC, nevertheless a literature review and our results indicate that i(9q) and robertsonian translocations are relevant findings.

P-946 Why do non smokers with non-small cell lung cancer (NSCLC) who receive erlotinib have better clinical outcomes than smokers?

Lung Cancer ◽  
2005 ◽  
Vol 49 ◽  
pp. S368 ◽  
Author(s):  
G. Clark ◽  
P. Cagnoni ◽  
M. Ptaszynski ◽  
M. Hamilton ◽  
P. Santabárbara ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Clinical Outcomes ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung
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