scholarly journals Case-cohort studies with interval-censored failure time data

Biometrika ◽  
2017 ◽  
Vol 104 (1) ◽  
pp. 17-29 ◽  
Author(s):  
Q. Zhou ◽  
H. Zhou ◽  
J. Cai
2021 ◽  
pp. 096228022110092
Author(s):  
Mingyue Du ◽  
Hui Zhao ◽  
Jianguo Sun

Cox’s proportional hazards model is the most commonly used model for regression analysis of failure time data and some methods have been developed for its variable selection under different situations. In this paper, we consider a general type of failure time data, case K interval-censored data, that include all of other types discussed as special cases, and propose a unified penalized variable selection procedure. In addition to its generality, another significant feature of the proposed approach is that unlike all of the existing variable selection methods for failure time data, the proposed approach allows dependent censoring, which can occur quite often and could lead to biased or misleading conclusions if not taken into account. For the implementation, a coordinate descent algorithm is developed and the oracle property of the proposed method is established. The numerical studies indicate that the proposed approach works well for practical situations and it is applied to a set of real data arising from Alzheimer’s Disease Neuroimaging Initiative study that motivated this study.


2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
June Liu ◽  
Yi Zhang

The case-cohort design is an effective and economical method in large cohort studies, especially when the disease rate is low. Case-cohort design in most of the existing literature is mainly used to analyze the univariate failure time data. But in practice, multivariate failure time data are commonly encountered in biomedical research. In this paper, we will propose methods based on estimating equation method for case-cohort designs for clustered survival data. By introducing the event failure rate, three different weight functions are constructed. Then, three estimating equations and parameter estimators are presented. Furthermore, consistency and asymptotic normality of the proposed estimators are established. Finally, the simulation results show that the proposed estimation procedure has reasonable finite sample behaviors.


2007 ◽  
Vol 26 (28) ◽  
pp. 5147-5161 ◽  
Author(s):  
Man-Hua Chen ◽  
Xingwei Tong ◽  
Jianguo Sun

Sign in / Sign up

Export Citation Format

Share Document