scholarly journals Iron Deficiency Protects Against Severe Plasmodium falciparum Malaria and Death in Young Children

2012 ◽  
Vol 54 (8) ◽  
pp. 1137-1144 ◽  
Author(s):  
M. Gwamaka ◽  
J. D. Kurtis ◽  
B. E. Sorensen ◽  
S. Holte ◽  
R. Morrison ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Iron Deficiency ◽  
Young Children ◽  
Falciparum Malaria ◽  
Plasmodium Falciparum Malaria

scholarly journals Atovaquone and Proguanil versus Amodiaquine for the Treatment of Plasmodium falciparum Malaria in African Infants and Young Children

2003 ◽  
Vol 37 (11) ◽  
pp. 1441-1447 ◽  
Author(s):  
S. Borrmann ◽  
J.-F. Faucher ◽  
T. Bagaphou ◽  
M. A. Missinou ◽  
R. K. Binder ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Young Children ◽  
Falciparum Malaria ◽  
Plasmodium Falciparum Malaria ◽  
Infants And Young Children

scholarly journals The ancient battle for iron: Our struggle with pathogens

2003 ◽  
Vol 25 (6) ◽  
pp. 15-18 ◽  
Author(s):  
Andrew Prentice ◽  
Conor Doherty ◽  
Joann McDermid ◽  
Sarah Atkinson ◽  
Sharon Cox
Keyword(s):  
Plasmodium Falciparum ◽  
Natural Selection ◽  
Young Children ◽  
Infectious Diseases ◽  
Medical Care ◽  
Falciparum Malaria ◽  
Rainy Season ◽  
Respiratory Infections ◽  
Plasmodium Falciparum Malaria ◽  
The Impact

Young children in rural Gambia face constant exposure to gastrointestinal and respiratory infections and, during the rainy season (July–November), suffer recurrent bouts of Plasmodium falciparum malaria. Within living memory, these conditions led to more than half of the children dying before their fifth birthday, providing a graphic demonstration of the impact that infectious diseases have had on our natural selection. Fortunately, these horrific statistics have been decreased greatly by improved medical care, especially through vaccination and anti-malarial therapies, but conditions such as these have inevitably left a powerful imprint on man's genetic make-up.

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