Off-label use of direct oral anticoagulants compared with warfarin for left ventricular thrombi after myocardial infarction

2021 ◽  
Author(s):  
Patrick Sulzgruber
Keyword(s):  
Myocardial Infarction ◽  
Oral Anticoagulants ◽  
Direct Oral Anticoagulants ◽  
Left Ventricular ◽  
Off Label Use ◽  
Off Label ◽  
Left Ventricular Thrombi ◽  
Label Use

scholarly journals Off-label Use of Direct Oral Anticoagulants Compared With Warfarin for Left Ventricular Thrombi

2020 ◽  
Vol 5 (6) ◽  
pp. 685 ◽  
Author(s):  
Austin A. Robinson ◽  
Cory R. Trankle ◽  
Grayson Eubanks ◽  
Christopher Schumann ◽  
Paul Thompson ◽  
...  
Keyword(s):  
Oral Anticoagulants ◽  
Direct Oral Anticoagulants ◽  
Left Ventricular ◽  
Off Label Use ◽  
Off Label ◽  
Left Ventricular Thrombi ◽  
Label Use

scholarly journals Will Direct Oral Anticoagulants Have a Chance in Prosthetic Valves?

2020 ◽  
Vol 15 ◽  
Author(s):  
Mahmoud Abdelnabi ◽  
Abdallah Almaghraby ◽  
Yehia Saleh
Keyword(s):  
Left Atrial Appendage ◽  
Oral Anticoagulants ◽  
Direct Oral Anticoagulants ◽  
Left Ventricular ◽  
Off Label Use ◽  
Off Label ◽  
Prosthetic Valves ◽  
Large Sector ◽  
Abundant Data ◽  
Left Ventricular Thrombi

Although there are abundant data highlighting the safety and efficacy of direct oral anticoagulants, to date, recent guidelines have limited their use to stroke prevention in patients with non-valvular AF, as well as in the prevention and treatment of venous thromboembolism and pulmonary embolism. Encouraging data about the off-label use of direct oral anticoagulants have been shown in several other indications, such as intracardiac thrombi, left ventricular thrombi and left atrial appendage, but a large sector of patients are still not addressed, such as valvular and prosthetic patients.

scholarly journals Off-label Use of Direct Oral Anticoagulants in Patients Receiving Surgical Mechanical and Bioprosthetic Heart Valves

2021 ◽  
Vol 4 (3) ◽  
pp. e211259
Author(s):  
Ankur Kalra ◽  
Sajjad Raza ◽  
Baqir Hasan Jafry ◽  
Harley E. King ◽  
Joseph A. Lahorra ◽  
...  
Keyword(s):  
Heart Valves ◽  
Oral Anticoagulants ◽  
Direct Oral Anticoagulants ◽  
Off Label Use ◽  
Bioprosthetic Heart Valves ◽  
Off Label ◽  
Label Use

scholarly journals Off-Label Use of Direct Oral Anticoagulants in Intracerebral Hemorrhage Patients With Prosthetic Valves

Stroke ◽  
2017 ◽  
Vol 48 (11) ◽  
pp. 3183-3186
Author(s):  
Seemant Chaturvedi ◽  
Carlos A. Molina ◽  
Magdy H. Selim ◽  
Hans-Christoph Diener ◽  
Stefan H. Hohnloser
Keyword(s):  
Intracerebral Hemorrhage ◽  
Oral Anticoagulants ◽  
Direct Oral Anticoagulants ◽  
Off Label Use ◽  
Off Label ◽  
Prosthetic Valves ◽  
Label Use

scholarly journals A Case Series of Direct Oral Anticoagulants Use in Post-Infarction Left Ventricular Thrombus

2021 ◽  
Vol 33 (4) ◽  
pp. 19-23
Author(s):  
Tarique S. Chachar ◽  
Nooraldaem Yousif ◽  
Khurshid Ahmed ◽  
Tajammul Hussain ◽  
Haitham Amin
Keyword(s):  
Vitamin K Antagonists ◽  
Oral Anticoagulants ◽  
Direct Oral Anticoagulants ◽  
Case Series ◽  
Left Ventricular ◽  
Left Ventricular Thrombus ◽  
Off Label Use ◽  
Mortality And Morbidity ◽  
Ventricular Thrombus ◽  
Current Guidelines

Left ventricular thrombus (LVT) is a known complication of acute myocardial infarction (AMI). Vitamin K antagonists such as Warfarin showed a reduction in associated mortality and morbidity and are indicated as anticoagulants of choice in current guidelines. Since their approval for clinical use, there has been a dramatic increase in off-label use of direct oral anti-coagulants (DOAC) for LVT. In this case series, the authors share their successful experience with DOAC in the treatment of LVT.

scholarly journals Off-Label Use of New Oral Anticoagulants

Stroke ◽  
2014 ◽  
Vol 45 (7) ◽  
pp. 2158-2159
Author(s):  
Carlos A. Molina ◽  
Magdy H. Selim
Keyword(s):  
Oral Anticoagulants ◽  
New Oral Anticoagulants ◽  
Off Label Use ◽  
Off Label ◽  
Label Use

scholarly journals DIRECT ORAL ANTICOAGULANTS ARE EFFECTIVE THERAPY IN TREATING LEFT VENTRICULAR THROMBI

2020 ◽  
Vol 75 (11) ◽  
pp. 948 ◽  
Author(s):  
Adil Yunis ◽  
Laura Seese ◽  
Blaise Stearns ◽  
Michael Genuardi ◽  
Floyd Thoma ◽  
...  
Keyword(s):  
Oral Anticoagulants ◽  
Direct Oral Anticoagulants ◽  
Left Ventricular ◽  
Effective Therapy ◽  
Left Ventricular Thrombi

scholarly journals Off-Label Use of Non-Vitamin K Antagonist Oral Anticoagulants

2017 ◽  
Vol 69 (20) ◽  
pp. 2577-2578
Author(s):  
Stijn P.G. van Vugt ◽  
Marc A. Brouwer ◽  
Freek W.A. Verheugt
Keyword(s):  
Vitamin K ◽  
Oral Anticoagulants ◽  
Vitamin K Antagonist ◽  
Off Label Use ◽  
Off Label ◽  
Label Use
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