scholarly journals 963Atherosclerotic risk factors are associated with coronary artery disease but not with ischemic stroke in adults with congenital heart disease

2017 ◽  
Vol 38 (suppl_1) ◽  
Author(s):  
J.P. Bokma ◽  
I. Zegstroo ◽  
J.M. Kuijpers ◽  
T.C. Konings ◽  
R.R. Van Kimmenade ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Ischemic Stroke ◽  
Coronary Artery ◽  
Congenital Heart ◽  
Artery Disease

Burden of Coronary Artery Disease in Adults With Congenital Heart Disease and Its Relation to Congenital and Traditional Heart Risk Factors

2009 ◽  
Vol 103 (10) ◽  
pp. 1445-1450 ◽  
Author(s):  
Georgios Giannakoulas ◽  
Konstantinos Dimopoulos ◽  
Reto Engel ◽  
Omer Goktekin ◽  
Zekeriya Kucukdurmaz ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Congenital Heart ◽  
Artery Disease

scholarly journals Cardioembolic Sources in Stroke Patients in South of Brazil

Thrombosis ◽  
2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Luiz Carlos Porcello Marrone ◽  
João Pedro Farina Brunelli ◽  
Ricardo Lutzky Saute ◽  
Gustavo Henrique Tomasi ◽  
Bianca Cecchele Madeira ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Heart Disease ◽  
Ischemic Stroke ◽  
Coronary Artery ◽  
Valvular Heart Disease ◽  
Oral Anticoagulants ◽  
Artery Disease ◽  
South Of Brazil ◽  
Toast Classification

Background. Stroke is a leading cause of mortality and disability in Brazil and around the world. Cardioembolism is responsible for nearly 30% of the origins of ischemic stroke. Methods. We analyzed data of 256 patients with cardioembolic ischemic stroke (according to TOAST classification) who were admitted into the Hospital São Lucas-PUCRS from October 2011 to January 2014. The cardioembolic subtype was divided into six subgroups: arrhythmias, valvular heart disease, coronary artery disease, cardiomyopathy, septal abnormalities, and intracardiac injuries. The prevalence of the most important cardiovascular risk factors and medications in use for prevention of systemic embolism by the time of hospital admission was analyzed in each patient. Results. Among 256 patients aged 60.2 +/− 6.9 years, 132 males, arrhythmias were the most common cause of cardioembolism corresponding to 50.7%, followed by valvular heart disease (17.5%) and coronary artery disease (16%). Hypertension (61.7%) and dyslipidemia (43.7%) were the most common risk factors. Less than 50% of patients with arrhythmias were using oral anticoagulants. Conclusions. Identifying the prevalence of cardioembolic stroke sources subgroups has become an increasingly important role since the introduction of new oral anticoagulants. In this study, arrhythmias (especially atrial fibrillation) were the main cause of cardioembolism.

Coronary artery disease screening in adults with congenital heart disease prior to cardiac surgery

2019 ◽  
Vol 14 (6) ◽  
pp. 895-900 ◽  
Author(s):  
Bradley Johnson ◽  
Matthew Buelow ◽  
Michael Earing ◽  
Scott Cohen ◽  
Peter Bartz ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Congenital Heart Disease ◽  
Cardiac Surgery ◽  
Heart Disease ◽  
Coronary Artery ◽  
Congenital Heart ◽  
Disease Screening ◽  
Artery Disease

scholarly journals Comorbidity as a mediator of depression in adults with congenital heart disease: A population-based cohort study

2020 ◽  
pp. 147451512092378
Author(s):  
Hsiao-Ling Yang ◽  
Nien-Tzu Chang ◽  
Jou-Kou Wang ◽  
Chun-Wei Lu ◽  
Yong-Chen Huang ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Congenital Heart ◽  
Adult Congenital Heart Disease ◽  
Complex Congenital Heart Disease ◽  
Chronic Obstructive ◽  
Adult Congenital ◽  
Artery Disease

Background The population of adults with congenital heart disease (CHD) has increased dramatically with a high prevalence of acquired cardiac and non-cardiac comorbidities. However, the relationship among congenital heart disease, physical comorbidities, and psychological health in this population is not well studied. Aims The purpose of this study was to investigate (a) the association between adult congenital heart disease and the occurrence of depression and (b) whether physical comorbidities mediated the association between congenital heart disease and the occurrence of depression. Methods This retrospective cohort study was followed from 1 January 2010–31 December 2013, based on the data from the National Health Insurance Research Database 2010 in Taiwan. We used mediation analysis in survival data to assess the mediated effect. The hazard ratios were adjusted by age, sex, area of residence, and estimated propensity scores. Results We recruited 2122 adult congenital heart disease patients and 8488 matched controls. Nearly half of patients diagnosed with simple congenital heart disease, 39.0% had complex congenital heart disease, and 11.2% had unclassified congenital heart disease. Adult congenital heart disease patients had a significantly higher risk of depression than matched controls (adjusted hazard ratio = 1.43 and 1.48, for all and complex congenital heart disease, respectively, p<0.05). Coronary artery disease and chronic obstructive pulmonary disease were the significant comorbidities mediating the relationship between adult congenital heart disease and depression, the proportions mediated by coronary artery disease or chronic obstructive pulmonary disease were 35.5% and 12.9%, respectively. Conclusions Helping patients to prevent psychological and physical acquired disease is imperative. Coronary artery disease is a potent mediator between congenital heart disease and depression, especially for patients with complex congenital heart disease.

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