scholarly journals Duplication of the entire 22.9 Mb human chromosome 21 syntenic region on mouse chromosome 16 causes cardiovascular and gastrointestinal abnormalities

2007 ◽  
Vol 16 (11) ◽  
pp. 1359-1366 ◽  
Author(s):  
Zhongyou Li ◽  
Tao Yu ◽  
Masae Morishima ◽  
Annie Pao ◽  
Jeffrey LaDuca ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Mouse Chromosome ◽  
Syntenic Region ◽  
Chromosome 21 ◽  
Chromosome 16 ◽  
Human Chromosome 21 ◽  
Gastrointestinal Abnormalities

GART, SON, IFNAR, and CRF2-4 genes cluster on human Chromosome 21 and mouse Chromosome 16

1993 ◽  
Vol 4 (6) ◽  
pp. 338-342 ◽  
Author(s):  
Suzanne Cheng ◽  
Georges Lutfalla ◽  
Gilles Uze ◽  
Ilya M. Chumakov ◽  
Katheleen Gardiner
Keyword(s):  
Human Chromosome ◽  
Mouse Chromosome ◽  
Chromosome 21 ◽  
Chromosome 16 ◽  
Human Chromosome 21

Use of Comparative Physical and Sequence Mapping to Annotate Mouse Chromosome 16 and Human Chromosome 21

Genomics ◽  
2001 ◽  
Vol 74 (1) ◽  
pp. 45-54 ◽  
Author(s):  
Mathew T. Pletcher ◽  
Tim Wiltshire ◽  
Deborah E. Cabin ◽  
Melissa Villanueva ◽  
Roger H. Reeves
Keyword(s):  
Human Chromosome ◽  
Mouse Chromosome ◽  
Chromosome 21 ◽  
Chromosome 16 ◽  
Sequence Mapping ◽  
Human Chromosome 21

scholarly journals Segmental Trisomy of Mouse Chromosome 17: Introducing an Alternative Model of Down’s Syndrome

2003 ◽  
Vol 4 (6) ◽  
pp. 647-652 ◽  
Author(s):  
Jiri Forejt ◽  
Tomáš Vacík ◽  
Sona Gregorová
Keyword(s):  
Human Chromosome ◽  
Mouse Chromosome ◽  
Trisomy 21 ◽  
Alternative Model ◽  
Chromosome 21 ◽  
Chromosome 17 ◽  
Human Chromosomes ◽  
Chromosome 16 ◽  
Human Chromosome 21 ◽  
Distal Chromosome

All of the mouse models of human trisomy 21 syndrome that have been studied so far are based on segmental trisomies, encompassing, to a varying extent, distal chromosome 16. Their comparison with one or more unrelated and non-overlapping segmental trisomies may help to distinguish the effects of specific triplicated genes from the phenotypes caused by less specific developmental instability mechanisms. In this paper, the Ts43H segmental trisomy of mouse chromosome 17 is presented as such an alternative model. The trisomy stretches over 32.5 Mb of proximal chromosome 17 and includes 486 genes. The triplicated interval carries seven blocks of synteny with five human chromosomes. The block syntenic to human chromosome 21 contains 20 genes.

StchMaps to Mouse Chromosome 16, Extending the Conserved Synteny with Human Chromosome 21

Genomics ◽  
1998 ◽  
Vol 49 (1) ◽  
pp. 156-157 ◽  
Author(s):  
Roger H. Reeves ◽  
Elizabeth Rue ◽  
Jingwei Yu ◽  
Fa-Ten Kao
Keyword(s):  
Human Chromosome ◽  
Mouse Chromosome ◽  
Chromosome 21 ◽  
Conserved Synteny ◽  
Chromosome 16 ◽  
Human Chromosome 21

Detailed mapping of the ERG–ETS2 interval of human chromosome 21 and comparison with the region of conserved synteny on mouse chromosome 16

Gene ◽  
2004 ◽  
Vol 324 ◽  
pp. 65-77 ◽  
Author(s):  
C.M. Owczarek ◽  
K.J. Portbury ◽  
M.P. Hardy ◽  
D.A. O'Leary ◽  
J. Kudoh ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Mouse Chromosome ◽  
Chromosome 21 ◽  
Conserved Synteny ◽  
Chromosome 16 ◽  
Human Chromosome 21
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