Gene Identification and Characterization of the Pyridoxine Degradative Enzyme 4-Pyridoxic Acid Dehydrogenase from the Nitrogen-fixing Symbiotic Bacterium Mesorhizobium loti MAFF303099

2008 ◽  
Vol 143 (5) ◽  
pp. 603-609 ◽  
Author(s):  
F. Ge ◽  
N. Yokochi ◽  
Y. Yoshikane ◽  
K. Ohnishi ◽  
T. Yagi
Keyword(s):  
Symbiotic Bacterium ◽  
Gene Identification ◽  
Nitrogen Fixing ◽  
Mesorhizobium Loti ◽  
Acid Dehydrogenase ◽  
Degradative Enzyme ◽  
Identification And Characterization

Gene Identification and Characterization of 5-Formyl-3-Hydroxy-2-Methylpyridine 4-Carboxylic Acid 5-Dehydrogenase, an NAD+-Dependent Dismutase

2009 ◽  
Vol 145 (4) ◽  
pp. 493-503 ◽  
Author(s):  
N. Yokochi ◽  
Y. Yoshikane ◽  
S. Matsumoto ◽  
M. Fujisawa ◽  
K. Ohnishi ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Gene Identification ◽  
Identification And Characterization

SCO-ping Out the Mechanisms Underlying the Etiology of Hydrocephalus

Physiology ◽  
2009 ◽  
Vol 24 (2) ◽  
pp. 117-126 ◽  
Author(s):  
Michael S. Huh ◽  
Matthew A. M. Todd ◽  
David J. Picketts
Keyword(s):  
Disease Gene ◽  
Subcommissural Organ ◽  
Clinical Problem ◽  
Gene Identification ◽  
Transgenic Mouse Models ◽  
Heterogeneous Nature ◽  
And Function ◽  
Identification And Characterization ◽  
Common Clinical Problem

The heterogeneous nature of congenital hydrocephalus has hampered our understanding of the molecular basis of this common clinical problem. However, disease gene identification and characterization of multiple transgenic mouse models has highlighted the importance of the subcommissural organ (SCO) and the ventricular ependymal (vel) cells. Here, we review how altered development and function of the SCO and vel cells contributes to hydrocephalus.

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