Role of Humoral Antibody and Infecting Dose in the Recovery of Rous Sarcoma Virus From Turkey Tumor Cells in Tissue Culture2

1962 ◽  
Keyword(s):  
Tissue Culture ◽  
Tumor Cells ◽  
Rous Sarcoma Virus ◽  
Humoral Antibody ◽  
Rous Sarcoma ◽  
Sarcoma Virus

Role of the mitogenic property and kinase activity of p60src in tumor formation by Rous sarcoma virus.

1984 ◽  
Vol 49 (2) ◽  
pp. 325-332 ◽  
Author(s):  
F Poirier ◽  
P Jullien ◽  
P Dezelee ◽  
G Dambrine ◽  
E Esnault ◽  
...  
Keyword(s):  
Rous Sarcoma Virus ◽  
Kinase Activity ◽  
Tumor Formation ◽  
Rous Sarcoma ◽  
Sarcoma Virus

scholarly journals COMPARATIVE STUDIES IN ROUS SARCOMA WITH VIRUS, TUMOR CELLS, AND CHICK EMBRYO CELLS TRANSFORMED IN VITRO BY VIRUS

1962 ◽  
Vol 115 (1) ◽  
pp. 245-251 ◽  
Author(s):  
Robert M. Dougherty ◽  
Herbert R. Morgan
Keyword(s):  
Chick Embryo ◽  
Tumor Cells ◽  
Comparative Studies ◽  
Rous Sarcoma Virus ◽  
Rous Sarcoma ◽  
Transformed Fibroblasts ◽  
Embryo Cells ◽  
Sarcoma Virus

Chick embryo fibroblasts infected in vitro with Rous sarcoma virus have properties similar to tumor cells when injected into virus-immune chickens. When such virus-transformed fibroblasts are injected into normal chickens, they apparently participate in the production of tumors independent of their release of virus and are thus apparently malignant in vivo.

scholarly journals Role of p60src kinase activity in the induction of neuroretinal cell proliferation by rous sarcoma virus.

1982 ◽  
Vol 42 (3) ◽  
pp. 780-789 ◽  
Author(s):  
F Poirier ◽  
G Calothy ◽  
R E Karess ◽  
E Erikson ◽  
H Hanafusa
Keyword(s):  
Cell Proliferation ◽  
Rous Sarcoma Virus ◽  
Kinase Activity ◽  
Rous Sarcoma ◽  
Sarcoma Virus

scholarly journals SPECIFIC TRANSPLANTATION IMMUNITY IN RELATION TO ROUS SARCOMA VIRUS TUMORIGENESIS IN MICE

1966 ◽  
Vol 123 (3) ◽  
pp. 487-503 ◽  
Author(s):  
Nils Jonsson ◽  
Hans Olof Sjögren
Keyword(s):  
Tumor Cells ◽  
Primary Tumor ◽  
Rous Sarcoma Virus ◽  
Transplantation Antigen ◽  
Transplantation Immunity ◽  
Primary Tumors ◽  
Clear Cut ◽  
Rous Sarcoma ◽  
Sarcoma Virus ◽  
Cut Resistance

Tests for transplantation immunity and for the occurrence of virus-neutralizing serum antibodies were performed on mice, inoculated when newborn with the Schmidt-Ruppin strain of Rous sarcoma virus (RSV-SR). Mice developing no palpable primary sarcomas showed a clear-cut resistance against the isografting of established specifically antigenic Rous tumors. Transplantation tests performed on primary tumor hosts after extirpation of the tumors revealed neither any clear-cut immunity nor tolerance to the specific transplantation antigen(s). Serial pretreatment of operated primary tumor animals with irradiated autologous or syngeneic tumor cells resulted in a clear-cut transplantation immunity. Virus-neutralizing activity was only found in a few sera from newborn infected mice, and in these cases there was no positive correlation with the transplantation immunity. It seems probable that a successful immunization against the RSV-SR specific transplantation antigen(s) prevents the development of primary tumors. There is no indication of any tolerance to this antigen in connection with the induction of primary tumors.

Sign in / Sign up

Export Citation Format

Share Document