COVID-19 infection presenting with acute epiglottitis

Abstract In this case report, we present a novel presentation of acute epiglottitis in a patient with severe acute respiratory syndrome—coronavirus 2 (SARS-CoV-2) who presented to the emergency room in extremis and respiratory failure requiring emergent cricothyrotomy. Epiglottitis has become less common since the introduction and widespread use of the Haemophilus influenzae type B (Hib) vaccine. This reduction in cases has shifted demographics of the disease from the pediatric population towards adults with comorbid conditions. Interestingly there is a high degree of overlap between many of the comorbidities between epiglottitis and COVID-19. The novel severe acute respiratory syndrome—coronavirus 2 (SARS-CoV-2), also referred to as coronavirus disease 19 (COVID-19), has been reported to affect the gastrointestinal tract and neural tissue and has been implicated in necrotizing encephalitis. We report the first known case of the novel SARS-CoV-2 virus presenting with acute epiglottitis.

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Side-effects and Immunogenicity of Haemophilus influenzae Type B Polysaccharide Vaccine in a Multiethnic Pediatric Population

Military Medicine ◽

10.1093/milmed/154.1.25 ◽

1989 ◽

Vol 154 (1) ◽

pp. 25-29 ◽

Cited By ~ 1

Author(s):

Lou A. Popejoy ◽

Awildal Rivera ◽

Ines Gonzales-Torres

Keyword(s):

Side Effects ◽

Haemophilus Influenzae ◽

Pediatric Population ◽

Polysaccharide Vaccine ◽

Haemophilus Influenzae Type ◽

Haemophilus Influenzae Type B ◽

Type B

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Influenzae b Epiglottitis and Meningitis

PEDIATRICS ◽

10.1542/peds.67.4.581 ◽

1981 ◽

Vol 67 (4) ◽

pp. 581-581

Author(s):

Stuart H. Walker

Keyword(s):

Haemophilus Influenzae ◽

Haemophilus Influenzae Type ◽

Haemophilus Influenzae Type B ◽

Type B ◽

Acute Epiglottitis

The report by Campbell et al1 extends the evidence that acute epiglottitis is pathogenetically different from other manifestations of bacteremic Haemophilus influenzae type b infection. Previously accumulated evidence indicating such a distinction includes. 1. Clinical Distinction. Epiglottitis almost never occurs in association with meningitis. Among the large number of cases of epiglottitis reported I can find but five instances2-6 in which a child with epiglottitis simultaneously or subsequently developed meningitis (and personally know of but one additional such case).

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Haemophilus influenzae Type b Vaccine: Use in the Pediatric Population

PEDIATRICS ◽

10.1542/peds.80.5.731 ◽

1987 ◽

Vol 80 (5) ◽

pp. 731-735

Author(s):

Vymutt J. Gururaj ◽

Jenny K. Patrick ◽

Patricia Fields Rogers

Keyword(s):

Health Professionals ◽

Private Practice ◽

Pediatric Population ◽

Health Department ◽

Haemophilus Influenzae Type ◽

Haemophilus Influenzae Type B ◽

Type B ◽

Community Clinics ◽

The University ◽

Teaching Clinics

To assess the use of the Haemophilus influenzae type b vaccine and the attitudes of health professionals regarding its use in the pediatric population, we conducted a study of community clinics, health department clinics, university-based teaching clinics, and private practice groups in the state of Texas. Whereas 59.6% of the private practice groups and 57.1% of the university-based teaching clinics administered the vaccine to more than 75% of their eligible children, 72.7% of community clinics and 81.7% of health department clinics never administered the vaccine to their eligible children. Likewise, whereas 100% of the university-based teaching clinics and 95.7% of the private practice groups had the vaccine available to their patients, only 22.7% of the community clinics and 15.5% of the health department clinics did so. The two most common reasons given by health professionals concerning the nonuse of the vaccine were nonavailability and high cost of the vaccine. Our findings suggest that a large segment of eligible children do not have access to this important vaccine and that children who depend on community and health department clinics for their routine health care are particularly affected in this regard. Strategies identified to increase the use of the vaccine include providing vaccine free of charge, increasing patient awareness of the vaccine benefits, and passing mandatory state laws requiring vaccine administration before day-care enrollment.

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