scholarly journals Immunology and Infectious Diseases

Author(s):  
Joti Juneja Mucci

An understanding of infectious diseases and immunology has a substantial role in the practice of critical care medicine, most commonly seen in sepsis or postoperative care. Infectious diseases are not a subject heavily emphasized in core anesthesiology training (the other being nutrition). In many instances, the intricate details of immunologic management are frequently relegated to consulting subspecialists by the average practicing intensivist. Familiarity with the content of this chapter allows an intensivist to demonstrate detailed knowledge of the management of patients with this pathology and of organ transplant recipients. This chapter has an additional emphasis on clinically challenging concepts that likely prepare the reader for practice as well as abstruse questions that could be present on the examination.


2019 ◽  
Vol 45 (5) ◽  
pp. 573-591 ◽  
Author(s):  
Jean-François Timsit ◽  
Romain Sonneville ◽  
Andre C. Kalil ◽  
Matteo Bassetti ◽  
Ricard Ferrer ◽  
...  


2017 ◽  
Vol 23 (8) ◽  
pp. 531-537 ◽  
Author(s):  
Yuhko Suzuki ◽  
Akira Kenjo ◽  
Tomiteru Togano ◽  
Natsuo Yamamoto ◽  
Hitoshi Ohto ◽  
...  


Author(s):  
Fu-Chi Yang ◽  
Hsiao-Mei Chen ◽  
Chiu-Mieh Huang ◽  
Pei-Lun Hsieh ◽  
Shoei-Shen Wang ◽  
...  

With recent advances in surgery and immunosuppressive drugs, organ transplantation has become a major treatment for irreversible organ failure. However, organ transplant recipients returning home after operation may face ongoing physiological, psychological, and social difficulties. To increase recipients’ quality of life, postoperative care at home is critical. Thus, the aim of this systematic literature review was to explore recipients’ difficulties and needs during postoperative care at home. Our search conformed to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and returned 23 relevant articles published from 1997–2020 in PubMed, MEDLINE, EBSCO, Cochrane, ProQuest, and CEPS, which were assessed using the Modified Jadad Scale or the 32 Consolidated Criteria for Reporting Qualitative Research (COREQ) appraisal indices and then synthesized through narration. The most common difficulties faced were psychological difficulties, followed by physiological, social, and other difficulties; the most common needs were psychological needs, followed by education and information training, social, and other needs. These results demonstrated that healthcare professionals can do more to provide patients with comprehensive care and promote successful self-management and quality of life at home. They also confirmed that collaboration between transplant teams, caregivers, and patients is necessary to optimize postoperative outcomes. We suggest that customized care may promote postoperative patients’ self-management and quality of life at home.



2016 ◽  
Vol 38 (2) ◽  
pp. 179-185 ◽  
Author(s):  
Claire Wintenberger ◽  
Daniele Maubon ◽  
Elena Charpentier ◽  
John Rendu ◽  
Patricia Pavese ◽  
...  

OBJECTIVETo determine the origin of grouped cases of Pneumocystis pneumonia in solid-organ transplant recipients at our institution.DESIGNA case series with clinical examinations, genotyping, and an epidemiological survey.SETTINGA university hospital in France.PATIENTSWe report 12 solid-organ transplant recipients with successive cases of Pneumocystis pneumonia that occurred over 3 years; 10 of these cases occurred in a single year.METHODSWe used molecular typing of P. jirovecii strains by multilocus sequence typing and clinical epidemiological survey to determine potential dates and places of transmission.RESULTSBetween May 2014 and March 2015, 10 solid-organ transplant recipients (5 kidney transplants, 4 heart transplants, and 1 lung transplant) presented with Pneumocystis pneumonia. Molecular genotyping revealed the same P. jirovecii strain in at least 6 patients. This Pneumocystis strain was not identified in control patients (ie, nontransplant patients presenting with pulmonary pneumocystosis) during this period. The epidemiological survey guided by sequencing results provided information on the probable or possible dates and places of contamination for 5 of these patients. The mobile infectious diseases unit played a coordination role in the clinical management (adaptation of the local guidelines) and epidemiological survey.CONCLUSIONOur cardiac and kidney transplant units experienced grouped cases of pulmonary pneumocystosis. Genotyping and epidemiological surveying results suggested interhuman contamination, which was quickly eliminated thanks to multidisciplinary coordination.Infect Control Hosp Epidemiol 2017;38:179–185



Sign in / Sign up

Export Citation Format

Share Document