Case 2.11

Author(s):  
Christine U. Lee ◽  
James F. Glockner

45-year-old woman with acute myelogenous leukemia having undergone several chemotherapeutic regimens Axial fat-suppressed FSE T2-weighted image (Figure 2.11.1) demonstrates several lobulated splenic masses and a more subtle lesion in the periphery of the right hepatic lobe. Axial IP and OP T1-weighted 2D SPGR (...

2000 ◽  
Vol 38 (9) ◽  
pp. 3375-3378 ◽  
Author(s):  
Peter C. Iwen ◽  
Stefano R. Tarantolo ◽  
Deanna A. Sutton ◽  
Michael G. Rinaldi ◽  
Steven H. Hinrichs

Cylindrocarpon lichenicola is a saprophytic soil fungus which has rarely been associated with human disease. We report the first case of localized invasive cutaneous infection caused by this fungus in a 53-year-old male from the rural midwestern United States with relapsed acute myelogenous leukemia. On admission for induction chemotherapy, the patient was noted to have an abrasive laceration between the fourth and fifth metacarpophalangeal joints and on the dorsum of the right hand, which progressed to frank ulceration following chemotherapy. A biopsy provided an initial diagnosis of an invasive fungal infection consistent with aspergillosis based on the histopathological appearance of the mold in tissue. Multiple positive fungal cultures which were obtained from the biopsied tissue were subsequently identified by microscopic and macroscopic characteristics to be C. lichenicola. The infection resolved following marrow regeneration, aggressive debridement of the affected tissue, and treatment with amphotericin B. This case extends the conditions associated with invasive disease caused by C. lichenicola.


2020 ◽  
Vol 54 (3) ◽  
Author(s):  
Veronica Marie E. Ramos ◽  
Charmaine Vanessa S. Chamberlin ◽  
Belen L. Dofitas

A 67-year-old female with acute myelogenous leukemia, presented with a two-week history of enlarging ecchymosis-like plaques with hemorrhagic bullae on the right forearm and anterior legs, associated with fever, pain, and swelling. Tissue cultures were persistently negative. Lesions progressed despite broad-spectrum antibiotic coverage. Histopathology showed neutrophilic dermatitis, consistent with pyoderma gangrenosum. The patient was diagnosed with the bullous type. This type is rare with only two reported cases in the Philippines since 2011. Systemic glucocorticoids were given with note of dramatic improvement of the lesions.


1985 ◽  
Vol 47 (1) ◽  
pp. 3-10 ◽  
Author(s):  
Shuichi INADA ◽  
Taizo KOHNO ◽  
Iseko SAKAI ◽  
Yoriko SHIMAMOTO ◽  
Nobutaka IMAMURA ◽  
...  

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