scholarly journals Intracranial myxoid mesenchymal neoplasms with EWSR1 gene rearrangement: report of 2 midline cases with one demonstrating durable response to MET inhibitor monotherapy

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Yanel De Los Santos ◽  
David Shin ◽  
Samuel Malnik ◽  
Marie Rivera-Zengotita ◽  
David Tran ◽  
...  
Keyword(s):  
Gene Rearrangement ◽  
Durable Response ◽  
Mesenchymal Neoplasms ◽  
Met Inhibitor ◽  
Ewsr1 Gene

Soft tissue myoepithelial carcinoma without EWSR1 gene rearrangement and poor outcome. A case report

2012 ◽  
Vol 45 (1) ◽  
pp. 58-63 ◽  
Author(s):  
María Auxiliadora Aparicio ◽  
Fernando López-Barea ◽  
Juan Jesús Cruz ◽  
María del Carmen García Macías ◽  
Teresa Hernández ◽  
...  
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Gene Rearrangement ◽  
Myoepithelial Carcinoma ◽  
Poor Outcome ◽  
Ewsr1 Gene

scholarly journals EWSR1 gene rearrangement occurs in a subset of cutaneous myoepithelial tumors: a study of 18 cases

2011 ◽  
Vol 24 (11) ◽  
pp. 1444-1450 ◽  
Author(s):  
Uta Flucke ◽  
Gabriele Palmedo ◽  
Nina Blankenhorn ◽  
Pieter J Slootweg ◽  
Heinz Kutzner ◽  
...  
Keyword(s):  
Gene Rearrangement ◽  
Ewsr1 Gene

Combined hepatocellular carcinoma and high grade neuroendocrine carcinoma with EWSR1 gene rearrangement

Pathology ◽  
2018 ◽  
Vol 50 (7) ◽  
pp. 779-782 ◽  
Author(s):  
Khoon Leong Chuah ◽  
Brendan Pang ◽  
Diana Lim ◽  
Chi Kuen Lee ◽  
Cora Yuk-Ping Chau
Keyword(s):  
Hepatocellular Carcinoma ◽  
Neuroendocrine Carcinoma ◽  
Gene Rearrangement ◽  
High Grade ◽  
Ewsr1 Gene

Blastic plasmacytoid dendritic cell neoplasm with EWSR1 gene rearrangement

2013 ◽  
Vol 67 (1) ◽  
pp. 90-92 ◽  
Author(s):  
Qinghua Cao ◽  
Fang Liu ◽  
Gang Niu ◽  
Ling Xue ◽  
Anjia Han
Keyword(s):  
Dendritic Cell ◽  
Gene Rearrangement ◽  
Plasmacytoid Dendritic Cell ◽  
Cell Neoplasm ◽  
Ewsr1 Gene

EWSR1-ATF1 Fusion in a Myoepithelial Carcinoma of Soft Tissue With Small Round Cell Morphology: A Potential Diagnostic Pitfall

2021 ◽  
pp. 109352662199886
Author(s):  
Bruce D Leckey ◽  
Ivy John ◽  
Miguel Reyes-Múgica ◽  
Rana Naous
Keyword(s):  
Soft Tissue ◽  
Cell Morphology ◽  
Gene Rearrangements ◽  
Myoepithelial Carcinoma ◽  
Round Cell ◽  
Genetic Event ◽  
Diagnostic Pitfall ◽  
Mesenchymal Neoplasms ◽  
Ewsr1 Gene ◽  
Difficult Cases

Myoepithelial tumors of soft tissue are rare mesenchymal neoplasms that overlap with their salivary gland and skin counterparts at both the histopathologic and molecular levels. EWSR1 gene rearrangements with various fusion partners represent a common genetic event in myoepithelial tumors of soft tissue, whether benign or malignant, and may prove useful as a diagnostic tool in difficult cases. However, the number of diagnostic entities with EWSR1 gene rearrangements has grown considerably in recent years, and there is significant morphologic and immunophenotypic overlap amongst this group, underscoring the importance of fusion testing to detect fusion partners that are characteristic of discrete diagnostic entities. Herein, we report a malignant myoepithelial tumor of soft tissue/myoepithelial carcinoma with an undifferentiated round cell morphology arising in a pediatric patient with a EWSR1-ATF1 gene fusion.

Malignant peritoneal mesothelioma associated with EWSR1 gene rearrangement

Pathology ◽  
2020 ◽  
Vol 52 ◽  
pp. S75-S76
Author(s):  
Michelyn Joan ◽  
Anthony J. Gill ◽  
James Kench ◽  
Cherry Koh ◽  
Renee C.F. Chan ◽  
...  
Keyword(s):  
Gene Rearrangement ◽  
Peritoneal Mesothelioma ◽  
Malignant Peritoneal Mesothelioma ◽  
Ewsr1 Gene

Malignant gastrointestinal neuroectodermal tumour (GNET): neural mesenchymal tumours of the gastrointestinal tract with striking histology and EWSR1 gene rearrangement

Pathology ◽  
2019 ◽  
Vol 51 (3) ◽  
pp. 324-327 ◽  
Author(s):  
Christopher W. Toon ◽  
Wendy Cooper ◽  
Christina Selinger ◽  
Christophe R. Berney ◽  
Jeanne Tomlinson
Keyword(s):  
Gastrointestinal Tract ◽  
Gene Rearrangement ◽  
Neuroectodermal Tumour ◽  
Ewsr1 Gene ◽  
Mesenchymal Tumours
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