Kindling the Spark: Early Development

Author(s):  
Joanne Haroutounian

Alullaby winds its way through the intimate confines of the nursery, as a restless baby is soothed to sleep. The rhythm and rocking chair synchronize a pulse as a mother sings softly to her child. The baby listens to the gentle flow of the melody, which drifts into a hum that vibrates against the sleeping child’s tiny head. A few short years later, Mom smiles as she looks in to her three-year-old’s room. Her daughter is nestled in the same rocking chair, singing a rather lopsided version of the same lullaby, gently stroking a rag doll wrapped in a frayed old baby blanket. Children listen before they are born. They are aware of their mother’s heartbeat and the different environmental sounds that filter into the cozy womb. They are surrounded by the low-pitched pulsating sounds of their mother’s cardiovascular system at work. Studies show that pregnant singers find their babies much quieter when they are singing. Instrumentalists report the opposite effect, with lots of internal activity when they are performing. Even before birth, a child recognizes the sound of a mother’s voice and responds to music or familiar sounds. Prenatal studies abound that can measure the movements and startle reflexes of these yet-to-be-born listeners. Loud, sudden noises (above 100 db) cause the fetal heart to beat faster and an immediate startle response. One experiment zapped 15 seconds of a Bach organ prelude (at 100 db) through headphones nestled close to a mother’s abdomen. Not surprisingly, the fetal heart rate accelerated within five seconds of this musical stimulation. Once a baby is born, the effects of these prenatal sounds still have an influence on behavior. Studies of newborns by Salk in the 1960s resulted in the popularity of crib devices that play the sound of an adult heartbeat to soothe babies to sleep. Other studies show the same soothing effect for seven-day-old neonates listening to taped sounds of intrauterine background noises. From birth, the mother’s voice is distinguished from other women’s voices and recognized more readily than the father’s voice—again stemming from prenatal listening experiences.

2007 ◽  
Vol 8 (4) ◽  
pp. 272-282 ◽  
Author(s):  
C.T. Lee ◽  
C.A. Brown ◽  
S.M.J. Hains ◽  
B.S. Kisilevsky

Recent observation of maternal voice recognition provides evidence of rudimentary memory and learning in healthy term fetuses. However, such higher order auditory processing has not been examined in the presence of maternal hypertension, which is associated with reduced and/or impaired uteroplacental blood flow. In this study, voice processing was examined in 40 fetuses (gestational ages of 33 to 41 weeks) of hypertensive and normotensive women. Fetuses received 2 min of no sound, 2 min of a tape-recorded story read by their mothers or by a female stranger, and 2 min of no sound while fetal heart rate was recorded. Results demonstrated that fetuses in the normotensive group had heart rate accelerations during the playing of their mother's voice, whereas the response occurred in the hypertensive group following maternal voice offset. Across all fetuses, a greater fetal heart rate change was observed when the amniotic fluid index was above compared to below the median (i.e., 150 mm), indicating that amniotic fluid volume may be an independent moderator of fetal auditory sensitivity. It was concluded that differential fetal responding to the mother's voice in pregnancies complicated by maternal hypertension may reflect functional elevation of sensorineural threshold or a delay in auditory system maturation, signifying functional differences during fetal life or subtle differences in the development of the central nervous system.


1987 ◽  
Vol 253 (6) ◽  
pp. R904-R909 ◽  
Author(s):  
C. E. Wood ◽  
C. Y. Cheung ◽  
R. A. Brace

The purpose of this study was to determine whether physiological amounts of cortisol affect the fetal cardiovascular system. Cortisol (4 micrograms/min) or the vehicle was infused intravenously for 5 h into six chronically catheterized sheep fetuses at 127-143 days gestation (term = 145-150 days). In the cortisol-infused animals, plasma cortisol concentration increased from 2.0 +/- 0.6 (SE) to 8.3 +/- 0.9 ng/ml. There was a concomitant decrease in fetal heart rate of 38 beats/min (P less than 1 X 10(-6)) and an increase in arterial pressure. Estimated blood volume decreased by 6% in the cortisol-infused fetuses compared with the vehicle-infused animals (P less than 1 X 10(-4]. In addition, plasma norepinephrine and epinephrine concentrations decreased to 70% of control at the end of the 5-h cortisol infusion, whereas plasma renin concentration decreased to 34% of control. The simultaneous increase in fetal arterial pressure and decrease in estimated blood volume suggest that fetal vascular resistance increased, whereas vascular compliance and/or nonstressed vascular volume decreased. However, this does not appear to be mediated by increases in circulating vasoconstrictor hormone concentrations or increased sympathetic tone. Thus the present study shows that physiological amounts of cortisol have significant effects on the fetal cardiovascular system but the mechanisms are unknown.


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