Life

Author(s):  
Tony J. Prescott

A core tenet of the emerging field of research in living machines is that biological entities that live and act—organisms—have much in common with certain kinds of man-made entities—machines—that can display autonomous behaviour. But underlying this parallel, which is made even more persuasive by observing the life-like behaviour of many of the artifacts described in this book, are a host of critical, and still only partially answered questions. Perhaps the most fundamental of these is “what is life?” This section of the Handbook of Living Machines delves into this core question, exploring some of the most fundamental properties of living systems, such as their capacity to self-organize, to evolve, to grow, to metabolize, to self-repair, and to reproduce. This introduction provides a brief discussion about the nature of life, seen from a systems perspective, followed by summaries of each of the contributed chapters in this section.

2014 ◽  
Vol 82 (2) ◽  
pp. 209-214 ◽  
Author(s):  
Christopher B. Forrest

Author(s):  
Christophe Jouis ◽  
Magali Roux-Rouquié ◽  
Jean-Gabriel Ganascia

Identical molecules could play different roles depending of the relations they may have with different partners embedded in different processes, at different time and/or localization. To address such intricate networks that account for the complexity of living systems, systems biology is an emerging field that aims at understanding such dynamic interactions from the knowledge of their components and the relations between these components. Among main issues in system biology, knowledge on entities spatial relations is of importance to assess the topology of biological networks. In this perspective, mining data and texts could afford specific clues. To address this issue we examine the use of contextual exploration method to develop extraction rules that can retrieve information on relations between biological entities in scientific literature. We propose the system Seekbio that could be plugged at Pubmed output as an interface between results of PubMed query and articles selection following spatial relationships requests.


2017 ◽  
Vol 73 (1) ◽  
Author(s):  
Petrus L. Steenkamp

The Netherdutch Reformed Church (Nederduitsch Hervormde Kerk van Afrika) finds itself in a precarious situation. It could be described as a watershed moment in the life of this denomination. The impasse developed due to various factors such as the loss of membership, the economic situation, ecumenical isolation and various other influences, which eventually resulted in a strong institutionalised organisation. Institutionalisation necessarily resulted in a shift of focus from the essence of being Church towards institutional continuation. As a result, the organic growth of the church suffered. This article investigates the institutionalism of the Netherdutch Reformed Church from an open (living) systems perspective, thereby identifying the dysfunctionality between form and function and ending with certain perspectives in respect of a change in focus by the church to realise the true essence of being Church of Jesus Christ.


2020 ◽  
Vol 2020 (1) ◽  
pp. 11533
Author(s):  
David Korten ◽  
Andrew J. Hoffman ◽  
Chris Laszlo ◽  
Michael Andreas Pirson ◽  
Sandra A. Waddock

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