Endocrinology: Ultrasonographic appearance of polycystic ovaries is associated with exaggerated ovarian androgen and oestradiol responses to gonadotrophin-releasing hormone agonist in women undergoing assisted reproduction treatment

1995 ◽  
Vol 10 (3) ◽  
pp. 513-519 ◽  
Author(s):  
Anne-Maria Suikkari ◽  
Vivien MacLachlan ◽  
Joseph Montalto ◽  
Ilan Calderon ◽  
David L. Healy ◽  
...  
Keyword(s):  
Assisted Reproduction ◽  
Polycystic Ovaries ◽  
Releasing Hormone ◽  
Gonadotrophin Releasing Hormone ◽  
Ultrasonographic Appearance ◽  
Assisted Reproduction Treatment

ABNORMAL LUTEINIZING HORMONE RESPONSE PATTERNS TO SYNTHETIC GONADOTROPHIN RELEASING HORMONE IN PATIENTS WITH POLYCYSTIC OVARIAN SYNDROME

1976 ◽  
Vol 70 (2) ◽  
pp. 163-171 ◽  
Author(s):  
M. KATZ ◽  
P. J. CARR
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Feedback Mechanism ◽  
Response Patterns ◽  
Hormone Response ◽  
Polycystic Ovaries ◽  
Releasing Hormone ◽  
Negative Feedback Mechanism ◽  
Gonadotrophin Releasing Hormone ◽  
Prolonged Response ◽  
Ovarian Syndrome

SUMMARY Basal gonadotrophin and sex steroid levels and responses to an intravenous injection of 100 μg gonadotrophin releasing hormone (Gn-RH) have been studied in 15 patients with polycystic ovaries. Mean basal LH concentration was raised and an excessive, exaggerated and prolonged response was observed after Gn-RH treatment, but patients could further be subdivided into two functional groups on the basis of their basal LH values and LH response patterns. Evidence was also produced which suggested a breakdown in the negative feedback mechanism in these patients.

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