scholarly journals Reliability of In Vitro Methods Used to Measure Intrinsic Clearance of Hydrophobic Organic Chemicals by Rainbow Trout: Results of an International Ring Trial

2018 ◽  
Vol 164 (2) ◽  
pp. 563-575 ◽  
Author(s):  
John Nichols ◽  
Kellie Fay ◽  
Mary Jo Bernhard ◽  
Ina Bischof ◽  
John Davis ◽  
...  
Keyword(s):  
Rainbow Trout ◽  
Intrinsic Clearance ◽  
Organic Chemicals ◽  
Hydrophobic Organic Chemicals ◽  
In Vitro Methods ◽  
Ring Trial

In vitro to in vivo extrapolation of biotransformation rates for assessing bioaccumulation of hydrophobic organic chemicals in mammals

2017 ◽  
Vol 36 (7) ◽  
pp. 1934-1946 ◽  
Author(s):  
Yung-Shan Lee ◽  
Justin C. Lo ◽  
S.Victoria Otton ◽  
Margo M. Moore ◽  
Chris J. Kennedy ◽  
...  
Keyword(s):  
Organic Chemicals ◽  
Hydrophobic Organic Chemicals ◽  
In Vivo Extrapolation

Hepatic Clearance Binding Terms of Hydrophobic Organic Chemicals in Rainbow Trout: Application of a Streamlined Sorbent-Phase Dosing Method

2020 ◽  
Vol 7 (9) ◽  
pp. 672-676
Author(s):  
Leslie J. Saunders ◽  
Gabrielle Diaz-Blanco ◽  
Yung-Shan Lee ◽  
S. Victoria Otton ◽  
Frank A. P. C. Gobas
Keyword(s):  
Rainbow Trout ◽  
Hepatic Clearance ◽  
Organic Chemicals ◽  
Hydrophobic Organic Chemicals ◽  
Sorbent Phase ◽  
Dosing Method

TOWARDS IMPROVED MODELS FOR PREDICTING BIOCONCENTRATION OF WELL-METABOLIZED COMPOUNDS BY RAINBOW TROUT USING MEASURED RATES OF IN VITRO INTRINSIC CLEARANCE

2013 ◽  
pp. n/a-n/a ◽  
Author(s):  
John W. Nichols ◽  
Duane B. Huggett ◽  
Jon A. Arnot ◽  
Patrick N. Fitzsimmons ◽  
Christina E. Cowan-Ellsberry
Keyword(s):  
Rainbow Trout ◽  
Intrinsic Clearance

Predicting the Bioconcentration of Fragrance Ingredients by Rainbow Trout Using Measured Rates of in Vitro Intrinsic Clearance

2014 ◽  
Vol 48 (16) ◽  
pp. 9486-9495 ◽  
Author(s):  
Heike Laue ◽  
Hans Gfeller ◽  
Karen J. Jenner ◽  
John W. Nichols ◽  
Susanne Kern ◽  
...  
Keyword(s):  
Rainbow Trout ◽  
Intrinsic Clearance

In vitro methods of assessing the viability of rainbow trout spermatozoa

1992 ◽  
Vol 38 (4) ◽  
pp. 679-686 ◽  
Author(s):  
M.A. McNiven ◽  
R.K. Gallant ◽  
G.F. Richardson
Keyword(s):  
Rainbow Trout ◽  
In Vitro Methods

Evaluation and comparison of in vitro intrinsic clearance rates measured using cryopreserved hepatocytes from humans, rats, and rainbow trout

Toxicology ◽  
2021 ◽  
pp. 152819
Author(s):  
Sherry R. Black ◽  
John W. Nichols ◽  
Kellie A. Fay ◽  
Sharlene R. Matten ◽  
Scott G. Lynn
Keyword(s):  
Rainbow Trout ◽  
Intrinsic Clearance ◽  
Clearance Rates

scholarly journals TransFEr: a new device to measure the transfer of volatile and hydrophobic organic chemicals across an in vitro intestinal fish cell barrier

2018 ◽  
Vol 10 (36) ◽  
pp. 4394-4403 ◽  
Author(s):  
Hannah Schug ◽  
Frédéric Begnaud ◽  
Christian Debonneville ◽  
Fabienne Berthaud ◽  
Sylvia Gimeno ◽  
...  
Keyword(s):  
Fish Cell ◽  
Organic Chemicals ◽  
Hydrophobic Organic Chemicals ◽  
New Device

Being able to quantify transfer of compounds across cellular barriers is important but challenging.

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