Medical education and training has evolved over the centuries. Ireland has a long history of leading on aspects of training that remain relevant today, focussing on the apprenticeship model coupled with a robust modern medical education framework. The practice of medicine is changing rapidly driven by expanding knowledge, advances in technology and use of artificial intelligence, demographic shifts and the expectations of patients and society. Medical training and education need to adapt to ensure that our current knowledge and future medical workforce is prepared for modern-day patient-centric practice. Ireland has emerged as a world leader in medical device technology, pharmaceutical research and development and social media technology support which offer the opportunity for the future of medical training. Knowledge, emotional intelligence, critical thinking, compassion, resilience and leadership are key attributes to which we as a profession aspire. There is an opportunity to leverage Ireland’s global position in technology and finance to train our modern-day medical workforce whilst retaining the attributes of the compassionate practice of the art of medicine. This paper explores the past, present and future of medical education and training in Ireland.