Recent advances in the assessment and treatment of psychotic affective disorders

1989 ◽  
Vol 2 (1) ◽  
pp. 7-11 ◽  
Author(s):  
P G Janicak
CNS Spectrums ◽  
1998 ◽  
Vol 3 (5) ◽  
pp. 21-37 ◽  
Author(s):  
Gabriele S. Leverich ◽  
Robert M. Post

AbstractThe recurrent and frequently chronic course of affective disorders requires careful delineation of the number, frequency, and pattern of prior and current episodes and their response to pharmacotherapies to help develop optimal assessment and treatment approaches for these Potentially lethal medical illnesses. To better track and monitor the longitudinal course of unipolar and bipolar illness and to promote more effective management, we developed the retrospective and prospective National Institute of Mental Health Life Chart Methodology (NIMH-LCM). The principles of retrospective and prospective life charting are the focus of this article. Following introductory background information on affective disorders, the influence of Kraepelin's work and his use of life charts are reviewed as the basis and framework for the NIMH-LCM. The use of life charting both retrospectively and prospectively is discussed, with examples of its utility and benefits.


Hand Surgery ◽  
2015 ◽  
Vol 20 (03) ◽  
pp. 352-365 ◽  
Author(s):  
Gregory Ian Bain ◽  
Chong Jin Yeo ◽  
Levi Philip Morse

Kienböck disease is a disorder of impaired lunate vascularity which ultimately has the potential to lead to marked degeneration of the wrist and impaired wrist function. The aetiology of the avascular necrosis is uncertain, but theories relate to ulnar variance, variability in lunate vascularity and intraosseous pressures. Clinical symptoms can be subtle and variable, requiring a high index of suspicion for the diagnosis. The Lichtmann classification has historically been used to guide management. We present a review of Kienböck disease, with a focus on the recent advances in assessment and treatment. Based on our understanding thus far of the pathoanatomy of Kienböck’s disease, we are proposing a pathological staging system founded on the vascularity, osseous and chondral health of the lunate. We also propose an articular-based approach to treatment, with an arthroscopic grading system to guide management.


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