IMPROVED TUMOR TARGETING OF A GENETICALLY ENGINEERED SINGLE-CHAIN Fv (sFv) OF THE PANCARCINOMA MONOCLONAL ANTIBODY (MAb) CC49 WHEN GIVEN IN COMBINATION WITH INTERFERON-GAMMA (IFY-γ)

C. Nieroda; D. Milenic; J. Schlom; J. W. Greiner

doi:10.1097/00002371-199410000-00042

IMPROVED TUMOR TARGETING OF A GENETICALLY ENGINEERED SINGLE-CHAIN Fv (sFv) OF THE PANCARCINOMA MONOCLONAL ANTIBODY (MAb) CC49 WHEN GIVEN IN COMBINATION WITH INTERFERON-GAMMA (IFY-γ)

Journal of Immunotherapy ◽

10.1097/00002371-199410000-00042 ◽

1994 ◽

Vol 16 (3) ◽

pp. 242

Author(s):

C. Nieroda ◽

D. Milenic ◽

J. Schlom ◽

J. W. Greiner

Keyword(s):

Monoclonal Antibody ◽

Interferon Gamma ◽

Tumor Targeting ◽

Genetically Engineered ◽

Single Chain ◽

Single Chain Fv

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Radiometal labeling of recombinant proteins by a genetically engineered minimal chelation site: technetium-99m coordination by single-chain Fv antibody fusion proteins through a C-terminal cysteinyl peptide.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.92.18.8358 ◽

1995 ◽

Vol 92 (18) ◽

pp. 8358-8362 ◽

Cited By ~ 37

Author(s):

A. J. George ◽

F. Jamar ◽

M. S. Tai ◽

B. T. Heelan ◽

G. P. Adams ◽

...

Keyword(s):

Recombinant Proteins ◽

Fusion Proteins ◽

Genetically Engineered ◽

Single Chain ◽

Technetium 99M ◽

Single Chain Fv ◽

Fv Antibody ◽

Single Chain Fv Antibody

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Single-Chain Fv Antibody Fragments Retain Binding Properties of the Monoclonal Antibody Raised Against Peptide P1 of the Human Prion Protein

Applied Biochemistry and Biotechnology ◽

10.1007/s12010-009-8699-4 ◽

2009 ◽

Vol 160 (6) ◽

pp. 1808-1821 ◽

Cited By ~ 16

Author(s):

Nives Škrlj ◽

Vladka Čurin Šerbec ◽

Marko Dolinar

Keyword(s):

Monoclonal Antibody ◽

Prion Protein ◽

Antibody Fragments ◽

Single Chain ◽

Binding Properties ◽

Single Chain Fv ◽

Fv Antibody ◽

Human Prion Protein ◽

Single Chain Fv Antibody

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Corrigendum to “Tumor-targeting CTL expressing a single-chain Fv specific for VEGFR2” [Biochem. Biophys. Res. Commun. 394 (2010) 54–58]

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2011.11.009 ◽

2012 ◽

Vol 417 (3) ◽

pp. 1106

Author(s):

Naoko Kanagawa ◽

Tatsuya Yanagawa ◽

Yohei Mukai ◽

Yasuo Yoshioka ◽

Naoki Okada ◽

...

Keyword(s):

Tumor Targeting ◽

Single Chain ◽

Single Chain Fv

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Tumor Targeting by a Multivalent Single-Chain Fv (scFv) Anti-Lewis Y Antibody Construct

Cancer Biotherapy & Radiopharmaceuticals ◽

10.1089/cbr.2007.0450 ◽

2008 ◽

Vol 23 (4) ◽

pp. 411-424 ◽

Cited By ~ 23

Author(s):

Marcus P. Kelly ◽

F.-T. Lee ◽

Kiki Tahtis ◽

Barbara E. Power ◽

Fiona E. Smyth ◽

...

Keyword(s):

Tumor Targeting ◽

Single Chain ◽

Single Chain Fv ◽

Lewis Y

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Synthesis, cloning and expression of the single-chain Fv gene of the HPr-specific monoclonal antibody, Jel42. Determination of binding constants with wild-type and mutant HPrs

Protein Engineering Design and Selection ◽

10.1093/protein/12.7.623 ◽

1999 ◽

Vol 12 (7) ◽

pp. 623-630 ◽

Cited By ~ 8

Author(s):

Joan E. Smallshaw ◽

Fawzy Georges ◽

Jeremy S. Lee ◽

E.Bruce Waygood

Keyword(s):

Monoclonal Antibody ◽

Binding Constants ◽

Cloning And Expression ◽

Specific Monoclonal Antibody ◽

Wild Type ◽

Single Chain ◽

Single Chain Fv

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A bacterial single-chain Fv antibody fragment that inhibits binding of its parental anti-E-Selectin monoclonal antibody to activated human endothelial cells

Journal of Biotechnology ◽

10.1016/s0168-1656(99)00005-x ◽

1999 ◽

Vol 72 (1-2) ◽

pp. 1-12 ◽

Cited By ~ 7

Author(s):

Racmar Casalvilla ◽

Marta Dueñas ◽

Marta Ayala ◽

Silian Cruz ◽

Liset Cruz ◽

...

Keyword(s):

Monoclonal Antibody ◽

Endothelial Cells ◽

Antibody Fragment ◽

Single Chain ◽

Human Endothelial Cells ◽

Single Chain Fv ◽

Fv Antibody ◽

Single Chain Fv Antibody

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Determinants of selective tumor targeting by single-chain Fv molecules

Immunotechnology ◽

10.1016/1380-2933(96)80684-1 ◽

1996 ◽

Vol 2 (1) ◽

pp. 73

Author(s):

L.M. Weiner ◽

J. Marks ◽

J. Huston ◽

R. Schierb ◽

J. McCartney ◽

...

Keyword(s):

Tumor Targeting ◽

Single Chain ◽

Single Chain Fv

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Tumor-targeting CTL expressing a single-chain Fv specific for VEGFR2

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2010.02.085 ◽

2010 ◽

Vol 394 (1) ◽

pp. 54-58 ◽

Cited By ~ 5

Author(s):

Naoko Kanagawa ◽

Tatsuya Yanagawa ◽

Yohei Mukai ◽

Yasuo Yoshioka ◽

Naoki Okada ◽

...

Keyword(s):

Tumor Targeting ◽

Single Chain ◽

Single Chain Fv

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A physiologically based pharmacokinetic (PBPK) model to characterize and predict the disposition of monoclonal antibody CC49 and its single chain Fv constructs

International Immunopharmacology ◽

10.1016/j.intimp.2007.10.023 ◽

2008 ◽

Vol 8 (3) ◽

pp. 401-413 ◽

Cited By ~ 70

Author(s):

Jasmine P. Davda ◽

Maneesh Jain ◽

Surinder K. Batra ◽

Peter R. Gwilt ◽

Dennis H. Robinson

Keyword(s):

Monoclonal Antibody ◽

Pbpk Model ◽

Single Chain ◽

Physiologically Based Pharmacokinetic ◽

Single Chain Fv ◽

Physiologically Based

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Generating improved single-chain Fv molecules for tumor targeting

Journal of Immunological Methods ◽

10.1016/s0022-1759(99)00161-1 ◽

1999 ◽

Vol 231 (1-2) ◽

pp. 249-260 ◽

Cited By ~ 101

Author(s):

Gregory P Adams ◽

Robert Schier

Keyword(s):

Tumor Targeting ◽

Single Chain ◽

Single Chain Fv

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