Fluorophotometric Assessment of Rabbit Corneal Epithelial Barrier Function After Rigid Contact Lens Wear

Cornea ◽  
1999 ◽  
Vol 18 (1) ◽  
pp. 87-91 ◽  
Author(s):  
Hideji Ichijima ◽  
Norihiko Yokoi ◽  
Aoi Nishizawa ◽  
Shigeru Kinoshita

1995 ◽  
Vol 35 ◽  
pp. S180
Author(s):  
T. Takahashi ◽  
Y. Enomoto ◽  
M. Itoi ◽  
N. Itoh ◽  
K. Nakayasu ◽  
...  


1994 ◽  
Vol 26 (3) ◽  
pp. 129-136 ◽  
Author(s):  
Ed.P.M. Boets ◽  
Martin J. Kerkmeer ◽  
Jaap A. van Best


2010 ◽  
Vol 33 ◽  
pp. S18-S23 ◽  
Author(s):  
M.E. Cavet ◽  
K.R. VanDerMeid ◽  
K.L. Harrington ◽  
R. Tchao ◽  
K.W. Ward ◽  
...  


2000 ◽  
Vol 214 (5) ◽  
pp. 332-336 ◽  
Author(s):  
Akiko Niiya ◽  
Norihiko Yokoi ◽  
Yasuhiro Matsumoto ◽  
Aoi Komuro ◽  
Takeshi Ishibashi ◽  
...  


2018 ◽  
Vol 2 (2) ◽  
pp. e14-e21
Author(s):  
Melissa Barnett ◽  
Jonathon Ross ◽  
Blythe Durbin-Johnson

Abstract Objectives: The purpose of this study was to evaluate the performance (i.e. vision, comfort and fit) of spherical and front-surface toric scleral lenses in subjects with regular, healthy corneas. Methods: Scleral lenses were fitin the eyes (n = 16) of healthy subjects (n = 9) with regular corneas, absent of pathology, and studied using an observational, multi-visit design. Lens fit was objectively evaluatedby an experienced practitioner.Following 1 month of successful lens wear, participants completedsubjective satisfaction surveys regarding the scleral lens wearing experience. Results:  According to participant surveys, scleral lenses were subjectively preferred over soft toric or gas permeable contact lenses in 88% of eyes, including in all eyes fit with a front-surface toric scleral lens (n = 3). Seventy-five percent (75%) of eyes achieved visual acuity of 0.1 logMAR or better, while all eyes with prior spectacle wear achieved visual acuity with a scleral lens within 1 Snellen line of spectacle correction. Seventy-five percent (75%) of eyes achieved good subjective comfort with a scleral lens. No participants reported poor subjective vision and/or comfort. Conclusions:  Our findings suggest that subjects preferred the performance of a scleral lens (spherical or front-surface toric) compared to a soft toric or gas permeable contact lens. Moreover, scleral lenses may provide a viable, alternative contact lens modality option for patients considering discontinuation of traditional soft toric and/or rigid contact lens wear; so long as the factors associated with hypoxia remain minimized. Key Words:  scleral lens; scleral contact lens; front-surface toric scleral lens; lens performance; normal eyes; healthy eyes



2020 ◽  
Vol 46 (1) ◽  
pp. 24-30
Author(s):  
Bi Yang ◽  
Longqian Liu ◽  
Pauline Cho


2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Naoto Tokuda ◽  
Yasushi Kitaoka ◽  
Akiko Matsuzawa ◽  
Ayaka Tsukamoto ◽  
Kana Sase ◽  
...  

Purpose. The aim of the present study was to examine the effects of switching from Latanoprost ophthalmic solution containing a preservative to preservative-free Tafluprost ophthalmic solution or Tafluprost containing a preservative on ocular surfaces. Materials and Methods. Forty patients (40 eyes) with glaucoma (mean age: 62.0 ± 10.9 years) using Latanoprost with preservative for six months or longer were assigned either to a Tafluprost-containing-preservative group (20 eyes) or preservative-free-Tafluprost group (20 eyes). The intraocular pressure, corneal epithelial barrier function (fluorescein uptake concentration with fluorophotometer FL-500), superficial punctate keratopathy (AD classification), and tear film breakup time (TBUT) were assessed before switching and at 12 weeks after switching. Results. No significant differences in intraocular pressure were noted after switching in either group. Corneal epithelial barrier function was improved significantly after switching in both the Tafluprost-containing-preservative and the preservative-free-Tafluprost groups. There were no significant differences in AD scores after switching in the Tafluprost-containing-preservative group, but significant improvements were noted in the preservative-free-Tafluprost group. No significant differences in TBUT were noted in the Tafluprost-containing-preservative or preservative-free-Tafluprost groups after switching. Conclusion. After switching from preservative Latanoprost to Tafluprost containing-preservative or preservative-free Tafluprost, corneal epithelial barrier function was improved while the intraocular pressure reduction was retained.



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