IS THERE AN ASSOCIATION BETWEEN BLOOD PRESSURE VARIABILITY AND TARGET ORGAN DAMAGE IN DIABETIC AND NON-DIABETIC HYPERTENSIVE PATIENTS?

2004 ◽  
Vol 22 (Suppl. 2) ◽  
pp. S367
Author(s):  
J. Carmona ◽  
P. Amado ◽  
N. Vasconcelos ◽  
J. Alves ◽  
M. C. Rodrigues ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Variability ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ ◽  
Hypertensive Patients

P804The significance of 24h blood pressure variability improvement regarding target organ damage indices three years after medical treatment initiation in essential hypertension

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
H Triantafyllidi ◽  
A Schoinas ◽  
D Benas ◽  
D Birba ◽  
D Voutsinos ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Medical Treatment ◽  
Blood Pressure Variability ◽  
Treatment Initiation ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Left Ventricular ◽  
Target Organ ◽  
Hypertensive Patients ◽  
Damage Indices

Abstract Background Blood pressure variability (BPV) has been associated with development, progression and severity of cardiac and vascular organ damage and with an increased risk of cardiovascular events and mortality, independently adding to cardiovascular risk, over and above the contribution of elevated mean BP levels. We aimed to explore any correlation between differences in BPV and target organ damage indices (TOD) in hypertensive patients three years after medical treatment initiation. Methods At baseline and before medical treatment initiation, we measured 24h average SBP and DBP as well as 24h systolic BPV after 24h ambulatory blood pressure monitoring (ABPM) in newly diagnosed and never treated hypertensive patients (n=171, mean age=52+12 years, 110 males, 24h average SBP/DBP=138+10/87+9 mmHg, 24h systolic BPV=15+3) who were also subjected to arterial stiffness by carotid-femoral pulse wave velocity (PWV), left ventricular hypertrophy by left ventricular mass index (LVMI) and coronary flow reserve (CFR) estimations. All the above tests were repeated approximately three years later after treatment initiation. Results Patients were characterized as controlled (n=113, mean age=54+12 years, 62 males, 24h average SBP/DBP=118+6/71+6 mmHg) or non-controlled hyperensives (n=58, mean age=48+11 years, 48 males, 24h average SBP/DBP=133+8/83+7 mmHg) based on ABPM results three years later (controlled BP=24h average BP<130/80 mmHg). In the whole population, 24h average SBP/DBP, systolic BPV (p<0.001) and LVMI (p=0.01) were decreased while systolic BPV difference was related with LVMI difference (r=0.27, p<0.001). In controlled hypertensives, 24h average SBP/DBP, systolic BPV (p<0.001) and LVMI (p=0.02) were decreased while systolic BPV difference was related with LVMI difference (r=0.35, p<0.001). In non-controlled hypertensives, 24h average SBP (p=0.001), DBP p<0.001) and systolic BPV (p=0.04) were decreased while PWV was increased (p=0.03) and no correlations were found between systolic BPV and TOD. Correlation between BPV and LVMI Conclusions It seems that antihypertensive-induced systolic BPV improvement relate with cardiovascular risk decrease occur only in the setting of blood pressure treated within normal limits and confirmed by ABPM. Our study confirms that left ventricular mass between other TOD primarily improves due to successful antihypertensive treatment.

scholarly journals Blood pressure variability and target organ damage in hypertensive patients in the area of Blida (Algeria)

2019 ◽  
Vol 11 (1) ◽  
pp. 98
Author(s):  
A. Bachir Cherif ◽  
M. Temmar ◽  
N. Dammene Debbih ◽  
S. Bennouar ◽  
A. Taleb ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Variability ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ ◽  
Hypertensive Patients

scholarly journals Central blood pressure variability is increased in hypertensive patients with target organ damage

2018 ◽  
Vol 20 (2) ◽  
pp. 266-272 ◽  
Author(s):  
Alejandro de la Sierra ◽  
Julia Pareja ◽  
Sergi Yun ◽  
Eva Acosta ◽  
Francesco Aiello ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Variability ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ ◽  
Central Blood Pressure ◽  
Hypertensive Patients

Essential hypertension: Diagnosis, assessment, and treatment

2020 ◽  
pp. 3753-3778
Author(s):  
Bryan Williams ◽  
John D. Firth
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Severe Hypertension ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ ◽  
Elevated Blood ◽  
Hypertensive Patients ◽  
Assessment And Treatment ◽  
Hypertension Diagnosis

Essential hypertension is invariably symptomless and usually detected by routine screening or opportunistic measurement of blood pressure. However, once a patient has been labelled as ‘hypertensive’ it is not uncommon for them to associate preceding symptoms to their elevated blood pressure. Some patients will claim that they can recognize when their blood pressure is elevated, usually on the basis of symptoms such as plethoric features, palpitations, dizziness, or a feeling of tension. Screening surveys have demonstrated that these symptoms occur no more commonly in untreated hypertensive patients than they do in the normotensive population. However, there are two important caveats to the symptomless nature of essential hypertension: (1) symptoms may develop as a consequence of target organ damage, (2) headache may be a feature of severe hypertension.

Correlation between blood pressure variability and subclinical target organ damage in patients with essential hypertension

2019 ◽  
Vol 34 (9) ◽  
pp. 641-647 ◽  
Author(s):  
Mostafa El Mokadem ◽  
Hesham Boshra ◽  
Yasser Abd el Hady ◽  
Amany Kasla ◽  
Ahmed Gouda
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Blood Pressure Variability ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ

Effects of third-generation β-blockers, atenolol or amlodipine on blood pressure variability and target organ damage in spontaneously hypertensive rats

2020 ◽  
Vol 38 (3) ◽  
pp. 536-545 ◽  
Author(s):  
Julieta S. Del Mauro ◽  
Paula D. Prince ◽  
Miguel A. Allo ◽  
Yanina Santander Plantamura ◽  
Marcela A. Morettón ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Variability ◽  
Spontaneously Hypertensive Rats ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ ◽  
Third Generation ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
Β Blockers
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