Successful Induction of Tolerance of Both Islets and Kidneys and Cure of Diabetes Following Vascularized Islet-Kidney Transplantation in Non-human Primates

2012 ◽  
Vol 94 (10S) ◽  
pp. 347
Author(s):  
V. A. Pathiraja ◽  
M. Tasaki ◽  
J. Scalea ◽  
A. Matar ◽  
R. Duran-Struuck ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Successful Induction ◽  
Induction Of Tolerance

Sequential Mixed Lymphocyte Culture after Kidney Transplantation: Induction of Tolerance or Sensitization

Nephron ◽  
1997 ◽  
Vol 75 (2) ◽  
pp. 166-170 ◽  
Author(s):  
P. Creemers ◽  
E. Du Toit ◽  
M.J.D. Cassidy ◽  
D. Kahn
Keyword(s):  
Kidney Transplantation ◽  
Mixed Lymphocyte Culture ◽  
Lymphocyte Culture ◽  
Induction Of Tolerance

SUCCESSFUL INDUCTION OF TOLERANCE OF PANCREATIC ISLETS BETWEEN MHC-MISMATCHED NONHUMAN PRIMATES.

2000 ◽  
Vol 69 (Supplement) ◽  
pp. S304-S305
Author(s):  
T. Kawai ◽  
H. Sogawa ◽  
M. Koulmada ◽  
D. Ko ◽  
J. Oneal ◽  
...  
Keyword(s):  
Pancreatic Islets ◽  
Nonhuman Primates ◽  
Successful Induction ◽  
Induction Of Tolerance

scholarly journals The Microbiota and Kidney Transplantation: Influence on the Graft

EMJ Urology ◽  
2021 ◽  
pp. 95-105
Author(s):  
Maurizio Salvadori ◽  
Aris Tsalouchos
Keyword(s):  
Kidney Transplantation ◽  
Microbial Community ◽  
Transplant Recipient ◽  
Acute Rejection ◽  
Immunosuppressive Drug ◽  
Kidney Graft ◽  
Protective Function ◽  
Indigenous Microbiota ◽  
Gut Microbial Community ◽  
Induction Of Tolerance

The gut microbial community may be associated with complications after kidney transplantation. The indigenous microbiota has a significant and protective function that influences the transplant recipient response. Genetic or environmental factors may modify the indigenous microbiota and pathobionts appear. In this condition, several disturbances of the kidney graft may be observed. These include acute rejection, infection, diarrhoea, disturbance in the induction of tolerance, and modification of immunosuppressive drug metabolism. Recently, the use of prebiotics, probiotics, and synbiotics has been demonstrated to be effective in normalising these conditions and in restoring the generation of the normal indigenous microbiota. An improved understanding of the function and composition of the indigenous microbiota may help in finding further solutions to stabilise the microbiota after kidney transplantation.

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