Search for a cure for idiopathic pulmonary fibrosis: is stem cell therapy a light at the end of a long tunnel?

2004 ◽  
Vol 10 (5) ◽  
pp. 376-377
Author(s):  
Om P Sharma
Respirology ◽  
2014 ◽  
Vol 19 (7) ◽  
pp. 950-951 ◽  
Author(s):  
Marilyn K. Glassberg ◽  
Rebecca L. Toonkel

2019 ◽  
Vol 9 (1) ◽  
pp. 6-16 ◽  
Author(s):  
Alexander Averyanov ◽  
Irina Koroleva ◽  
Mikhail Konoplyannikov ◽  
Veronika Revkova ◽  
Victor Lesnyak ◽  
...  

2011 ◽  
Vol 9 (1) ◽  
pp. 182 ◽  
Author(s):  
Argyris Tzouvelekis ◽  
George Koliakos ◽  
Paschalis Ntolios ◽  
Irene Baira ◽  
Evangelos Bouros ◽  
...  

2013 ◽  
Vol 06 (08) ◽  
pp. 24-31 ◽  
Author(s):  
Zheng Wang ◽  
Xiaoju Zhang ◽  
Yi Kang ◽  
Yanli Zeng ◽  
Hongmei Liu ◽  
...  

2018 ◽  
Vol 27 (11) ◽  
pp. 1581-1587 ◽  
Author(s):  
Hong-Meng Chuang ◽  
Tina Emily Shih ◽  
Kang-Yun Lu ◽  
Sheng-Feng Tsai ◽  
Horng-Jyh Harn ◽  
...  

Although the clinical application of new drugs has been shown to be effective in slowing disease progression and improving the quality of life in patients with pulmonary fibrosis, the damaged lung tissue does not recover with these drugs. Thus, there is an urgent need to establish regenerative therapy, such as stem cell therapy or tissue engineering. Moreover, the clinical application of mesenchymal stem cell (MSC) therapy has been shown to be safe in humans with idiopathic pulmonary fibrosis (IPF). It seems that a combination of MSC transplantation and pharmaceutical therapy might have additional benefits; however, the experimental design for its efficacy is still lacking. In this review, we provide an overview of the mechanisms that were identified when IPF was treated with MSC transplantation or new drugs. To maximize the therapeutic effect, we suggest that MSC transplantation is combined with drug application for synergistic effects. This review provides clinicians and scientists with the most efficient medical options, in the hope that this will spur on future research and lead to an eventual cure for this disease.


2020 ◽  
Vol 53 (12) ◽  
Author(s):  
Zhongwen Li ◽  
Shuaishuai Niu ◽  
Baojie Guo ◽  
Tingting Gao ◽  
Lei Wang ◽  
...  

2014 ◽  
Vol 40 (3) ◽  
pp. 117-125 ◽  
Author(s):  
Sang Hoon Lee ◽  
Eun Joo Lee ◽  
Sang Yeub Lee ◽  
Je Hyeong Kim ◽  
Jae Jeong Shim ◽  
...  

2011 ◽  
Vol 17 (5) ◽  
pp. 368-373 ◽  
Author(s):  
Argyris Tzouvelekis ◽  
Antonis Antoniadis ◽  
Demosthenes Bouros

2014 ◽  
Vol 7 (1) ◽  
pp. 33-42 ◽  
Author(s):  
Marwa Mohammed Sabry ◽  
Seham Abd-Elhamed Elkalawy ◽  
Rahma Kamal El-din Abo-Elnour ◽  
Dalia Fathy Abd-El-Maksod

Sign in / Sign up

Export Citation Format

Share Document