Systematic Review of Anterior Interbody Fusion Techniques for Single- and Double-Level Cervical Degenerative Disc Disease

Spine ◽  
2011 ◽  
Vol 36 (14) ◽  
pp. E950-E960 ◽  
Author(s):  
Wilco Jacobs ◽  
Paul C. Willems ◽  
Moyo Kruyt ◽  
Jacques van Limbeek ◽  
Patricia G. Anderson ◽  
...  
Keyword(s):  
Systematic Review ◽  
Degenerative Disc Disease ◽  
Interbody Fusion ◽  
Disc Disease ◽  
Degenerative Disc ◽  
Anterior Interbody Fusion ◽  
Cervical Degenerative Disc Disease

scholarly journals Single or double-level anterior interbody fusion techniques for cervical degenerative disc disease

2004 ◽  
Author(s):  
Wilco Jacobs ◽  
Patricia G Anderson ◽  
Jacques van Limbeek ◽  
Paul C Willems ◽  
Paul Pavlov ◽  
...  
Keyword(s):  
Degenerative Disc Disease ◽  
Interbody Fusion ◽  
Disc Disease ◽  
Degenerative Disc ◽  
Anterior Interbody Fusion ◽  
Cervical Degenerative Disc Disease

scholarly journals Titanium-interlayer mediated hydroxyapatite coating on polyetheretherketone: a prospective study in patients with single-level cervical degenerative disc disease

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Ce Zhu ◽  
Miaomiao He ◽  
Lili Mao ◽  
Tao Li ◽  
Li Zhang ◽  
...  
Keyword(s):  
Degenerative Disc Disease ◽  
Fusion Rate ◽  
Peek Cage ◽  
Disc Disease ◽  
Degenerative Disc ◽  
Single Level ◽  
Cervical Degenerative Disc Disease ◽  
Post Operation

Abstract Background Currently, there are limited reports regarding investigation of the biological properties of polyetheretherketone (PEEK) coated with titanium (Ti) and hydroxyapatite (HA) in human. The objective of this study is to evaluate the in vivo response of the PEEK cages coated with Ti and HA versus uncoated PEEK cages after anterior cervical discectomy and fusion (ACDF) in patients with single-level cervical degenerative disc disease (CDDD). Methods Twenty-four patients with PEEK cages coated with Ti and HA (PEEK/Ti/HA group) were matched one-to-one with patients with uncoated PEEK cages (PEEK group) based on age, gender, and operative segment. All patients had been followed up for more than 2 years. Radiological assessments included intervertebral height (IH), C2-7 angle (C2-7a), segmental alignment (SA), and fusion rate. Clinical parameters included Visual Analogue Scale (VAS) and Japanese Orthopedic Association (JOA) scores. Results There was no statistical difference in SA, IH, and C2-7a between the two groups before and after surgery and all these parameters were restored postoperatively. The fusion rate of PEEK/Ti/HA group was significantly higher than PEEK group at 3-month post-operation (87.5% vs. 62.5%). At the last follow-up, the fusion rate of the both groups achieved 100%. The VAS and JOA scores were comparable between two groups and improved postoperatively. Conclusions In patients with single-level ACDF, PEEK cage coated with Ti and HA provided a higher fusion rate than uncoated PEEK cage at 3-month post-operation, while both two cages could achieve solid osseous fusion at the last follow up. Compared with the uncoated PEEK cage, PEEK/Ti/HA cage yielded similar favorable segmental and overall cervical lordosis, IH, and clinical outcomes after the surgery.

Evidence-based use of arthroplasty in cervical degenerative disc disease

2019 ◽  
Vol 43 (4) ◽  
pp. 767-775 ◽  
Author(s):  
Andrei F. Joaquim ◽  
Melvin C. Makhni ◽  
K. Daniel Riew
Keyword(s):  
Degenerative Disc Disease ◽  
Evidence Based ◽  
Disc Disease ◽  
Degenerative Disc ◽  
Cervical Degenerative Disc Disease

Long-term outcome of fusion for degenerative disc disease in the lumbar spine

2019 ◽  
Vol 101-B (12) ◽  
pp. 1526-1533 ◽  
Author(s):  
Peter Endler ◽  
Per Ekman ◽  
Ivan Berglund ◽  
Hans Möller ◽  
Paul Gerdhem
Keyword(s):  
Back Pain ◽  
Lumbar Spine ◽  
Degenerative Disc Disease ◽  
Interbody Fusion ◽  
Patient Reported Outcome ◽  
Posterolateral Fusion ◽  
Disc Disease ◽  
Degenerative Disc ◽  
Additional Surgery ◽  
Patient Reported

AimsChronic low back pain due to degenerative disc disease is sometimes treated with fusion. We compared the outcome of three different fusion techniques in the Swedish Spine Register: noninstrumented posterolateral fusion (PLF), instrumented posterolateral fusion (IPLF), and interbody fusion (IBF).Patients and MethodsA total of 2874 patients who were operated on at one or two lumbar levels were followed for a mean of 9.2 years (3.6 to 19.1) for any additional lumbar spine surgery. Patient-reported outcome data were available preoperatively (n = 2874) and at one year (n = 2274), two years (n = 1958), and a mean of 6.9 years (n = 1518) postoperatively and consisted of global assessment and visual analogue scales of leg and back pain, Oswestry Disability Index, EuroQol five-dimensional index, 36-Item Short-Form Health Survey, and satisfaction with treatment. Statistical analyses were performed with competing-risks proportional hazards regression or analysis of covariance, adjusted for baseline variables.ResultsThe number of patients with additional surgery were 32/183 (17%) in the PLF group, 229/1256 (18%) in the IPLF group, and 439/1435 (31%) in the IBF group. With the PLF group as a reference, the hazard ratio for additional lumbar surgery was 1.16 (95% confidence interval (CI) 0.78 to 1.72) for the IPLF group and 2.13 (95% CI 1.45 to 3.12) for the IBF group. All patient-reported outcomes improved after surgery (p < 0.001) but were without statistically significant differences between the groups at the one-, two- and 6.9-year follow-ups (all p ≥ 0.12).ConclusionThe addition of interbody fusion to posterolateral fusion was associated with a higher risk for additional surgery and showed no advantages in patient-reported outcome Cite this article: Bone Joint J 2019;101-B:1526–1533

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