Teriparatide Accelerates Lumbar Posterolateral Fusion in Women With Postmenopausal Osteoporosis

Spine ◽  
2012 ◽  
Vol 37 (23) ◽  
pp. E1464-E1468 ◽  
Author(s):  
Seiji Ohtori ◽  
Gen Inoue ◽  
Sumihisa Orita ◽  
Kazuyo Yamauchi ◽  
Yawara Eguchi ◽  
...  
Keyword(s):  
Postmenopausal Osteoporosis ◽  
Posterolateral Fusion ◽  
Lumbar Posterolateral Fusion

scholarly journals Does Discontinuing Teriparatide Treatment and Replacing It with Bisphosphonate Maintain the Volume of the Bone Fusion Mass after Lumbar Posterolateral Fusion in Women with Postmenopausal Osteoporosis?

2017 ◽  
Vol 11 (2) ◽  
pp. 272-277 ◽  
Author(s):  
Seiji Ohtori ◽  
Sumihisa Orita ◽  
Kazuyo Yamauchi ◽  
Yawara Eguchi ◽  
Yasuchika Aoki ◽  
...  
Keyword(s):  
Postmenopausal Osteoporosis ◽  
Degenerative Spondylolisthesis ◽  
Case Series ◽  
Posterolateral Fusion ◽  
Retrospective Case ◽  
Bone Fusion ◽  
Teriparatide Treatment ◽  
The Right ◽  
Mass Volume ◽  
Lumbar Posterolateral Fusion

<sec><title>Study Design</title><p>Retrospective case series.</p></sec><sec><title>Purpose</title><p>The purpose of this study was to determine whether discontinuing teriparatide treatment and replacing it with bisphosphonate treatment maintains the volume of the fusion mass after posterolateral fusion (PLF) in women with postmenopausal osteoporosis.</p></sec><sec><title>Overview of Literature</title><p>Clinical data support the efficacy of parathyroid hormone (PTH) for lumbar PLF. However, the use of PTH is limited to 2 years.</p></sec><sec><title>Methods</title><p>We treated 19 women diagnosed with osteoporosis and degenerative spondylolisthesis with teriparatide (20 µg daily subcutaneously). All patients underwent one-level instrumented PLF. Teriparatide was used during 2 months prior to surgery and more than 8 months after surgery. After discontinuing teriparatide treatment, all patients used bisphosphonate (17.5 mg risedronate weekly, oral administration). Area of the fusion mass across the transverse processes at one segment was determined on an anteroposterior radiograph at 1, 2, and 3 years after surgery.</p></sec><sec><title>Results</title><p>We followed 19 patients for 3 years. The average duration of teriparatide treatment was 11.5 months. The bone union rate was 95%. The average area of the bone fusion mass was not significantly different between the right and left sides at 1, 2, or 3 years after surgery (<italic>p</italic>&gt;0.05).</p></sec><sec><title>Conclusions</title><p>This study showed that replacing teriparatide treatment with bisphosphonate maintained the bone fusion mass volume after PLF in women with postmenopausal osteoporosis.</p></sec>

scholarly journals Feasibility and effects of a self-assembling peptide as a scaffold in bone healing: An in vivo study in rabbit lumbar posterolateral fusion and tibial intramedullary models

2018 ◽  
Vol 36 (12) ◽  
pp. 3285-3293 ◽  
Author(s):  
Kei Ando ◽  
Shiro Imagama ◽  
Kazuyoshi Kobayashi ◽  
Kenyu Ito ◽  
Mikito Tsushima ◽  
...  
Keyword(s):  
Bone Healing ◽  
Posterolateral Fusion ◽  
In Vivo Study ◽  
Self Assembling ◽  
Lumbar Posterolateral Fusion

The Role of Spinal Instrumentation in Augmenting Lumbar Posterolateral Fusion

Spine ◽  
1996 ◽  
Vol 21 (3) ◽  
pp. 278-287 ◽  
Author(s):  
Yoshihisa Kotani ◽  
Bryan W. Cunningham ◽  
Andrew Cappuccino ◽  
Kiyoshi Kaneda ◽  
Paul C. McAfee
Keyword(s):  
Spinal Instrumentation ◽  
Posterolateral Fusion ◽  
Lumbar Posterolateral Fusion

scholarly journals Comparison of the Bone Union Rates Using a Local Autobone and Bone Graft Substitute Mixed Graft in Lumbar Posterolateral Fusion

2020 ◽  
Vol 55 (2) ◽  
pp. 169
Author(s):  
Young-Chul Ko ◽  
Seong-Hwak Hong ◽  
Man-Jun Park ◽  
Jung-Wook Huh ◽  
Joon-Hyung Park ◽  
...  
Keyword(s):  
Bone Graft ◽  
Bone Graft Substitute ◽  
Bone Union ◽  
Posterolateral Fusion ◽  
Lumbar Posterolateral Fusion

Lumbar Posterolateral Fusion Using Demineralized Bone Matrix

2007 ◽  
Vol 14 (4) ◽  
pp. 256
Author(s):  
Sang Wook Bae ◽  
Ho Yoon Kwak ◽  
Jae Yoon Kim ◽  
Joo Sun Jung
Keyword(s):  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Posterolateral Fusion ◽  
Lumbar Posterolateral Fusion ◽  
Demineralized Bone

Effect of Critical Pathway of Lumbar Posterolateral Fusion in Spinal Stenosis

2002 ◽  
Vol 37 (3) ◽  
pp. 392 ◽  
Author(s):  
Hae Ok Park ◽  
Kyu Jung Cho ◽  
Rye Sup Kim ◽  
Suk Myun Ko ◽  
Jae Cheol Kim ◽  
...  
Keyword(s):  
Spinal Stenosis ◽  
Posterolateral Fusion ◽  
Critical Pathway ◽  
Lumbar Posterolateral Fusion

Outcome of Different Grafted Bone in Lumbar Posterolateral Fusion

2003 ◽  
Vol 10 (2) ◽  
pp. 82
Author(s):  
Kyu-Yeol Lee ◽  
Sung-Keun Sohn ◽  
Myung-Jin Lee ◽  
Sung-Hoo Kim
Keyword(s):  
Posterolateral Fusion ◽  
Lumbar Posterolateral Fusion
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