scholarly journals SAFETY AND EFFICACY OF ORAL FLUORESCEIN ANGIOGRAPHY IN DETECTING MACULAR EDEMA IN COMPARISON WITH SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY

Retina ◽  
2013 ◽  
Vol 33 (8) ◽  
pp. 1574-1583 ◽  
Author(s):  
Giulio Barteselli ◽  
Jay Chhablani ◽  
Su Na Lee ◽  
Haiyan Wang ◽  
Sharif El Emam ◽  
...  
Ophthalmology ◽  
2009 ◽  
Vol 116 (6) ◽  
pp. 1158-1167 ◽  
Author(s):  
Ling Yeung ◽  
Verônica Castro Lima ◽  
Patricia Garcia ◽  
Gennady Landa ◽  
Richard B. Rosen

Folia Medica ◽  
2016 ◽  
Vol 57 (3-4) ◽  
pp. 207-215 ◽  
Author(s):  
Vesela T. Mitkova-Hristova ◽  
Marieta I. Konareva-Kostianeva ◽  
Arsenia M. Balian ◽  
Nina S. Stoyanova ◽  
Maria A. Semerdzhieva

AbstractAIM: To compare spectral-domain optical coherence tomography (SD-OCT) with fluorescein angiography (FA) in detecting macular edema in patients with uveitis and analyse discrepancies in the findings obtained by the two methods. METHODS: The study included 133 eyes from 117 patients with uveitis that had SD-OCT (RTVue-100/ Optovue) and FA (Topcon TRC 50DX) scans performed to detect or rule out macular edema. RESULTS: Macular edema was found in 57 (42.9%) of the 133 surveyed eyes. In 37 eyes (27.8%) macular edema was confirmed by both imaging methods. In 17 eyes (12.8%) macular edema was detected on SD-OCT but not on FA;in 15 eyes of these the edema was diffuse, and in 2 eyes - serous retinal detachment was verified in the macular area. Focal macular edema was detected on FA in three eyes (2.3%) in which SD-OCT showed normal finding. In 76 eyes (57.1%) no pathological changes in the macula were observed on both SD-OCT and FA. Kappa coefficient was 0.675 at p < 0.001. The agreement rate between the two methods calculated using Kendall’s tau-b was 0.693 at p < 0.001. CONCLUSION: Fluorescein angiography and spectral domain optical coherence tomography are highly sensitive methods used in detecting macular edema in patients with uveitis, but they might fail to be efficient in this if used independently. Optical coherence tomography is a more informative method, especially in diagnosing diffuse macular edema.


2019 ◽  
Vol 2 ◽  
pp. 1 ◽  
Author(s):  
Anibal Martin Folgar ◽  
Jorge Oscar Zarate

We present a 57-year-old referred reduced visual acuity who was in treatment with paclitaxel for developing metastatic breast adenocarcinoma. Ophthalmoscopic examination, optical coherence tomography, and autofluorescence show the cystoid macular edema, but fluorescein angiography is normal, without leakage of dye in the late times. The patient responds well 8 weeks after stopping antineoplastic. Paclitaxel can cause cystoid macular edema and lifting a recovery both anatomical and functional of the macula.


Author(s):  
Sandeep Saxena ◽  
Levent Akduman ◽  
Carsten H. Meyer

AbstractAdvances in spectral-domain optical coherence tomography (SD-OCT) technology have enhanced the understanding of external limiting membrane (ELM) and ellipsoid zone (EZ) in diabetic macular edema. An increase in VEGF has been demonstrated to be associated with sequential ELM and EZ disruption on SD-OCT. An intact ELM is a prerequisite for an intact EZ in DME. Anti-VEGF therapy leads to restoration of barrier effect of ELM. The ELM restores first followed by EZ restoration.


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