An unusual case of bilateral macular detachment preceding renal failure

ABSTRACT A case is described of a man of 48, who presented a history and clinical picture of a solitary thyro-hypophysial syndrome with malignant exophthalmos but in which general connective tissue changes were found on histological and histochemical examination of the retrobulbar connective tissue and muscles, of the pretibial connective and muscle tissue and the nasal epithelium. The intraocular tension was increased. In addition, renal failure developed. The use of cortisol locally in the eyes had a beneficial effect on the eye syndrome. Systemic treatment with corticotrophin and prednisolone had an evident beneficial effect on the renal condition.

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Acute renal failure caused by pheniramine maleate induced rhabdomyolysis: An unusual case

Indian Journal of Critical Care Medicine ◽

10.4103/0972-5229.60176 ◽

2009 ◽

Vol 13 (4) ◽

pp. 221-223 ◽

Cited By ~ 4

Author(s):

Gunchan Paul ◽

P. Sood ◽

B. S. Paul ◽

S. Puri

Keyword(s):

Renal Failure ◽

Acute Renal Failure ◽

Unusual Case ◽

Pheniramine Maleate

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Management of obstructive renal failure caused by bilateral renal aspergilloma in an immunocompetent newborn

Journal of Medical Microbiology ◽

10.1099/jmm.0.012799-0 ◽

2010 ◽

Vol 59 (3) ◽

pp. 367-369 ◽

Cited By ~ 11

Author(s):

J. D. Martinez-Pajares ◽

M. C. Martinez-Ferriz ◽

D. Moreno-Perez ◽

M. Garcia-Ramirez ◽

S. Martin-Carballido ◽

...

Keyword(s):

Renal Failure ◽

Renal Function ◽

Amphotericin B ◽

Unusual Case ◽

Bladder Exstrophy ◽

Rare Condition ◽

Antifungal Drugs ◽

Fungal Colonization ◽

Premature Babies ◽

Obstructive Renal Failure

Fungal infection of the kidneys is a rare condition that has been reported in premature babies and in diabetic or immunocompromised adult patients. Candida spp. is the most frequent micro-organism involved. This paper reports a case of an immunocompetent newborn with a bladder exstrophy who suffered from an acute renal failure caused by bilateral renal aspergilloma (Aspergillus flavus). The newborn was treated with amphotericin B urinary tract irrigation through bilateral nephrostomy catheters, combined with liposomal amphotericin B and voriconazole therapy, which improved his renal function. However, due to persistent fungal colonization, a long antifungal treatment and permanent ureterostomies were necessary to deal with new episodes of ureterorenal obstruction. As of November 2009, despite the renal injuries, renal function had been conserved. The management of the mechanical obstruction and the choice of antifungal drugs are discussed in this unusual case.

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Acute Liver and Renal Failure: A Rare Adverse Effect Exclusive to Intravenous form of Amiodarone

Case Reports in Critical Care ◽

10.1155/2016/5232804 ◽

2016 ◽

Vol 2016 ◽

pp. 1-4 ◽

Cited By ~ 2

Author(s):

Robin Paudel ◽

Prerna Dogra ◽

Saurav Suman ◽

Saurav Acharya ◽

Jyoti Matta

Keyword(s):

Adverse Effect ◽

Renal Failure ◽

Drug Toxicity ◽

Unusual Case ◽

Renal Toxicity ◽

Wide Spectrum ◽

Polysorbate 80 ◽

Ventricular Tachyarrhythmias ◽

Case Review ◽

Idiosyncratic Reaction

Amiodarone is an antiarrhythmic drug which is highly effective against a wide spectrum of ventricular tachyarrhythmias making it irreplaceable in certain group of patients. We report an unusual case of acute liver and renal failure within 24 hours of initiation of intravenous (IV) amiodarone which resolved after stopping the medication. The mechanism of acute liver and renal toxicity is not clearly known but is believed to be secondary to amiodarone induced (relative) hypotension, idiosyncratic reaction to the drug, and toxicity of the vector that carries the medication, polysorbate-80. In this case review, we discuss the hyperacute drug toxicity caused by IV amiodarone being a distinctly different entity compared to the adverse effects shown by oral amiodarone and support the suggestion that oral amiodarone can be safely administered even in patients who manifest acute hepatitis with the IV form.

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