Analysis of a Continuous Series of 34 Young Patients With Early-Stage Cervical Cancer Selected for a Vaginal Radical Trachelectomy

2013 ◽  
Vol 23 (2) ◽  
pp. 331-336 ◽  
Author(s):  
Catherine Uzan ◽  
Sebastien Gouy ◽  
Delphine Desroque ◽  
Christophe Pomel ◽  
Pierre Duvillard ◽  
...  
Author(s):  
Jérémie Belghiti ◽  
Amélia Favier ◽  
Catherine Uzan ◽  
Stéphanie Motton ◽  
Geoffroy Canlorbe ◽  
...  

2021 ◽  
Author(s):  
Marlene Kranawetter ◽  
Christoph Grimm ◽  
Helena M Obermair ◽  
Valentina Paspalj ◽  
Alexander Reinthaller ◽  
...  

Abstract Purpose Radical trachelectomy is a viable option to preserve fertility for young patients with early cervical cancer. The aim of this study was to report surgical, oncological and obstetric outcomes of patients treated with radical abdominal trachelectomy at our institution. Methods A retrospective chart analysis and telephone survey for all patients with early stage cervical cancer treated with a radical abdominal trachelectomy and pelvic lymphadenectomy between 2007 and 2019 at the Department of Obstetrics and Gynaecology at the Medical University of Vienna, Austria was performed. Results Radical abdominal trachelectomy with pelvic lymph-node dissection was attempted for 22 patients. Four cases required conversion to radical hysterectomy due to positive resection margins and two cases required primary chemo-radiotherapy due to positive lymph nodes. Sixteen successfully abdominal radical trachelectomies preserving fertility were performed with two of these patients treated with neo-adjuvant chemotherapy. With a median follow-up time of 21.5 (6.5- 57.25) months, one patient (4.5%) had disease recurrence and subsequently died from cervical cancer. Six patients attempted to conceive, with a resulting four pregnancies with a live birth rate of 75%. Conclusion Abdominal radical trachelectomy is a safe procedure for women with early stage cervical cancer who desire fertility preservation. Surgery should be performed at a high volume gynaeco-oncological center.


2016 ◽  
Vol 26 (1) ◽  
pp. 163-168 ◽  
Author(s):  
Yoshifumi Kasuga ◽  
Hiroshi Nishio ◽  
Kei Miyakoshi ◽  
Suguru Sato ◽  
Juri Sugiyama ◽  
...  

2010 ◽  
Vol 17 (6) ◽  
pp. S6
Author(s):  
M.K. Kim ◽  
C.H. Choi ◽  
T. Song ◽  
H.S. Park ◽  
Y-Y. Lee ◽  
...  

2021 ◽  
pp. ijgc-2020-001782
Author(s):  
Blanca Segarra-Vidal ◽  
Jan Persson ◽  
Henrik Falconer

Radical trachelectomy is the ‘cornerstone’ of fertility-sparing surgery in patients with early-stage cervical cancer wishing to preserve fertility. Growing evidence has demonstrated the oncologic safety and subsequent favorable pregnancy outcomes in well-selected cases. In the absence of prospective trials, the decision on the appropriate surgical approach (vaginal, open, or minimally invasive surgery) should be based on local resources and surgeons’ preferences. Radical trachelectomy has the potential to preserve fertility in a large proportion of women with early-stage cervical cancer. However, prematurity and premature rupture of membranes are common obstetric complications after radical trachelectomy for cervical cancer. A multidisciplinary approach is crucial to optimize the balance between oncologic and obstetric outcomes. The purpose of this review is to provide an updated overview of the technical, oncologic, and obstetric aspects of radical trachelectomy.


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