Long-term Incidence and Degree of Sensorineural Hearing Loss in Otosclerosis

Background: Several otologic conditions can present with fluctuating sensorineural hearing loss, including Ménière’s disease, autoimmune inner ear disease, and enlarged vestibular aqueduct. Although these 3 etiologies vary greatly, distinguishing between these conditions at initial presentation can be challenging. Furthermore, initial treatment of these conditions is often similar. In this review, we discuss historical and current perspectives on diagnosis and treatment of these conditions. Summary: A literature search was performed regarding fluctuating hearing loss, and current treatment of these etiologies of fluctuating hearing loss was summarized. Immediate measures at the onset of acute hearing loss include corticosteroid therapy, while preventative and chronic therapies, which can limit disease severity and frequency, vary based on the specific condition treated. Key Messages: Fluctuating hearing loss can represent a range of pathologies, but the precise etiology may not be clear at initial presentation. Timely treatment and long-term follow-up, along with appropriate diagnostics, are necessary to optimize long-term hearing.

Download Full-text

Third-generation bisphosphonates for cochlear otosclerosis stabilizes sensorineural hearing loss in long-term follow-up

Laryngoscope Investigative Otolaryngology ◽

10.1002/lio2.91 ◽

2017 ◽

Vol 2 (5) ◽

pp. 262-268 ◽

Cited By ~ 1

Author(s):

Taha A. Jan ◽

Aaron K. Remenschneider ◽

Christopher Halpin ◽

Margaret Seton ◽

Michael J. McKenna ◽

...

Keyword(s):

Hearing Loss ◽

Sensorineural Hearing Loss ◽

Sensorineural Hearing ◽

Third Generation ◽

Long Term Follow Up

Download Full-text

A001 The importance of a periodic and long term audiological evaluation and ENT assessment in all the children affected by Kawasaki disease. Description of a case of progressive sensorineural hearing loss in a child with Kawasaki Disease (KD)

International Journal of Pediatric Otorhinolaryngology ◽

10.1016/s0165-5876(11)00191-1 ◽

2011 ◽

Vol 75 ◽

pp. 1

Author(s):

M.A. Clavería ◽

P. Clarós ◽

J. Lacima ◽

J. Anton ◽

J. Gambettola ◽

...

Keyword(s):

Hearing Loss ◽

Kawasaki Disease ◽

Sensorineural Hearing Loss ◽

Sensorineural Hearing

Download Full-text

The Short- and Long-Term Outcome of Intratympanic Steroid Therapy as a Salvage Treatment for Acute Low-Tone Sensorineural Hearing Loss without Episodes of Vertigo

Audiology and Neurotology ◽

10.1159/000444577 ◽

2016 ◽

Vol 21 (3) ◽

pp. 132-140 ◽

Cited By ~ 4

Author(s):

Shinya Morita ◽

Yuji Nakamaru ◽

Keishi Fujiwara ◽

Keiji Iizuka ◽

Masayori Masuya ◽

...

Keyword(s):

Hearing Loss ◽

Sensorineural Hearing Loss ◽

Salvage Treatment ◽

Sensorineural Hearing ◽

Control Group ◽

Long Term Follow Up ◽

Low Tone ◽

Hearing Outcomes

Objectives: To evaluate the hearing outcomes of intratympanic steroid (ITS) treatment for patients with acute low-tone sensorineural hearing loss (ALHL) after failure of initial therapy and to investigate the recurrence and progression to definite Ménière's disease (MD) during a long-term follow-up. Methods: We retrospectively reviewed the medical records of 90 patients with refractory ALHL who were followed up for at least 1 year between January 2000 and April 2014. Patients who responded poorly to initial medical treatment received intratympanic dexamethasone injections (ITS group) or isosorbide administration for 4 weeks (diuretic group) as salvage treatment options according to their choice of management. The control group did not receive ITS or the diuretic, due to their refusal of both medical treatments. The hearing outcomes were evaluated 1 month, 1 year and 5 years after the completion of the second-line therapy, and the rates of recurrence and progression to MD were measured during a follow-up period of at least 1 year. Results: Twenty-seven patients in the ITS group, 39 patients in the diuretic group and 24 patients in the control group were enrolled. Of these, 12 patients in the ITS group, 15 patients in the diuretic group and 12 patients in the control group were followed up for over 5 years. We found that the recovery rates and the audiometric functional values after 1 month and 1 year in the ITS group were significantly higher than those in the diuretic and control groups. However, there were no significant differences in the recovery rates or the audiometric functional values after 5 years, or in the rates of recurrence and progression to MD between the groups. Conclusions: Salvage ITS therapy can provide a relatively good short-term hearing outcome for ALHL patients who have persistent hearing loss despite conventional treatment. However, both recurrence and progression to MD after treatment were observed in some patients during the long-term follow-up.

Download Full-text