Correlation and Comparison of the Model for End-stage Liver Disease, Portal Pressure, and Serum Sodium for Outcome Prediction in Patients With Liver Cirrhosis

2007 ◽  
Vol 41 (7) ◽  
pp. 706-712 ◽  
Author(s):  
Ying-Wen Wang ◽  
Teh-Ia Huo ◽  
Ying-Ying Yang ◽  
Ming-Chih Hou ◽  
Pui-Ching Lee ◽  
...  



2007 ◽  
Vol 27 (4) ◽  
pp. 498-506 ◽  
Author(s):  
Teh-Ia Huo ◽  
Ying-Wen Wang ◽  
Ying-Ying Yang ◽  
Han-Chieh Lin ◽  
Pui-Ching Lee ◽  
...  


2015 ◽  
Vol 28 (2) ◽  
pp. 457
Author(s):  
MuhammadAbdEl Hamid Shatat ◽  
IbrahimM Boghdady ◽  
TarekE Korah ◽  
KhaledM Amin Elzorkany


Author(s):  
Dhawal Vyas

Background: The aim of the study was to evaluate the prevalence of hyponatremia in liver cirrhosis and the correlation between serum sodium and the Model for End-Stage Liver Disease (MELD) score in patients with liver cirrhosis. Methods: We prospectively collected data of 200 patients of chronic liver disease hospitalized in medical and surgical gastroenterology department of Geetanjali medical college, Udaipur. Results: Serum sodium values were strongly associated with severity of cirrhosis, assessed by child Pugh class and MELD score. There was significant relationship between serum sodium, renal function (as assessed by serum creatinine) Conclusion: Hyponatremia is a common problem in liver cirrhosis, especially advanced cirrhosis. The study showed that there is an association between hyponatremia and the presence of certain complications of liver cirrhosis. Also hyponatremia was associated with a higher severity of cirrhosis assessed by MELD scores.  Keywords: hyponatrenia, Liver cirrhosis, MELD score



Author(s):  
Ahmed Abdelrahman Mohamed Baz ◽  
Rana Magdy Mohamed ◽  
Khaled Helmy El-kaffas

Abstract Background Liver cirrhosis is a multi-etiological entity that alters the hepatic functions and vascularity by varying grades. Hereby, a cross-sectional study enrolling 100 cirrhotic patients (51 males and 49 females), who were diagnosed clinically and assessed by model for end-stage liver disease (MELD) score, then correlated to the hepatic Doppler parameters and ultrasound (US) findings of hepatic decompensation like ascites and splenomegaly. Results By Doppler and US, splenomegaly was evident in 49% of patients, while ascites was present in 44% of them. Increased hepatic artery velocity (HAV) was found in70% of cases, while 59% showed reduced portal vein velocity (PVV). There was a statistically significant correlation between HAV and MELD score (ρ = 0.000), but no significant correlation with either hepatic artery resistivity index (HARI) (ρ = 0.675) or PVV (ρ =0.266). Moreover, HAV had been correlated to splenomegaly (ρ = 0.000), whereas HARI (ρ = 0.137) and PVV (ρ = 0.241) did not significantly correlate. Also, ascites had correlated significantly to MELD score and HAV (ρ = 0.000), but neither HARI (ρ = 0.607) nor PVV (ρ = 0.143) was significantly correlated. Our results showed that HAV > 145 cm/s could confidently predict a high MELD score with 62.50% and 97.62 % sensitivity and specificity. Conclusion Doppler parameters of hepatic vessels (specifically HAV) in addition to the US findings of hepatic decompensation proved to be a non-invasive and cost-effective imaging tool for severity assessment in cirrhotic patients (scored by MELD); they could be used as additional prognostic parameters for improving the available treatment options and outcomes.





2002 ◽  
Vol 97 (11) ◽  
pp. 2855-2860 ◽  
Author(s):  
Edoardo Giannini ◽  
Federica Botta ◽  
Emanuela Testa ◽  
Paola Romagnoli ◽  
Simone Polegato ◽  
...  


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