A prospective 12-week mucosal healing assessment of small bowel Crohn’s disease as detected by capsule endoscopy

2014 ◽  
Vol 26 (11) ◽  
pp. 1253-1259 ◽  
Author(s):  
Barry J. Hall ◽  
Grainne E. Holleran ◽  
Sinead M. Smith ◽  
Nasir Mahmud ◽  
Deirdre A. McNamara
Keyword(s):  
Crohn’S Disease ◽  
Small Bowel ◽  
Crohn's Disease ◽  
Capsule Endoscopy ◽  
Mucosal Healing ◽  
Healing Assessment

scholarly journals A prospective 52week mucosal healing assessment of small bowel Crohn's disease as detected by capsule endoscopy

2014 ◽  
Vol 8 (12) ◽  
pp. 1601-1609 ◽  
Author(s):  
Barry Hall ◽  
Grainne Holleran ◽  
Jun-Liong Chin ◽  
Sinead Smith ◽  
Barbara Ryan ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Small Bowel ◽  
Crohn's Disease ◽  
Capsule Endoscopy ◽  
Mucosal Healing ◽  
Healing Assessment

scholarly journals Evaluation of mucosal healing in Small Bowel Crohn’s disease treated with Certolizumab Pegol assessed by wireless capsule endoscopy

2016 ◽  
Vol 2 (11) ◽  
Author(s):  
Ira Shafran ◽  
Patricia Burgunder ◽  
Renee DePanicis ◽  
Kara Fitch ◽  
Sally Hewit ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Small Bowel ◽  
Crohn's Disease ◽  
Capsule Endoscopy ◽  
Certolizumab Pegol ◽  
Mucosal Healing ◽  
Wireless Capsule Endoscopy ◽  
Wireless Capsule

scholarly journals Panenteric capsule endoscopy identifies proximal small bowel disease guiding upstaging and treatment intensification in Crohn’s disease: A European multicentre observational cohort study

2020 ◽  
pp. 205064062094866 ◽  
Author(s):  
Foong Way D Tai ◽  
Pierre Ellul ◽  
Alfonso Elosua ◽  
Ignacio Fernandez-Urien ◽  
Gian E Tontini ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Small Bowel ◽  
Crohn's Disease ◽  
Capsule Endoscopy ◽  
Bowel Disease ◽  
Mucosal Healing ◽  
Small Bowel Disease ◽  
Treatment Intensification ◽  
Non Invasive ◽  
Proximal Small Bowel

Background Endoscopically defined mucosal healing in Crohn’s disease is associated with improved outcomes. Panenteric capsule endoscopy enables a single non-invasive assessment of small and large bowel mucosal inflammation. Aims and methods: This multicentre observational study of patients with suspected and established Crohn’s disease examined the feasibility, safety and impact on patient outcomes of panenteric capsule endoscopy in routine clinical practice. The potential role in assessment of disease severity and extent by a comparison with existing clinical and biochemical markers is examined. Results Panenteric capsule endoscopy was performed on 93 patients (71 with established and 22 with suspected Crohn’s disease). A complete examination occurred in 85% (79/93). Two cases (2.8%) of capsule retention occurred in patients with established Crohn’s disease. Panenteric capsule resulted in management change in 38.7% (36/93) patients, including 64.6% (32/48) of those with an established diagnosis whose disease was active, and all three patients with newly diagnosed Crohn’s disease. Montreal classification was upstaged in 33.8% of patients with established Crohn’s disease and mucosal healing was demonstrated in 15.5%. Proximal small bowel disease upstaged disease in 12.7% and predicted escalation of therapy (odds ratio 40.3, 95% confidence interval 3.6–450.2). Raised C-reactive protein and faecal calprotectin were poorly sensitive in detecting active disease (0.48 and 0.59 respectively). Conclusions Panenteric capsule endoscopy was feasible in routine practice and the ability to detect proximal small bowel disease may allow better estimation of prognosis and guide treatment intensification. Panenteric capsule endoscopy may be a suitable non-invasive endoscopic investigation in determining disease activity and supporting management decisions.

Tu1141 Mucosal Healing of Small Bowel Crohn's Disease After Anti-TNFα Therapy Assessed by Capsule Endoscopy

2013 ◽  
Vol 144 (5) ◽  
pp. S-773 ◽  
Author(s):  
Nadezda Machkova ◽  
Dana Duricova ◽  
Martin Bortlik ◽  
Ludek Hrdlicka ◽  
Martin Lukas ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Small Bowel ◽  
Crohn's Disease ◽  
Capsule Endoscopy ◽  
Mucosal Healing

A prospective 24-week mucosal healing and deep remission assessment of small bowel and colonic Crohn's disease as detected by colon capsule endoscopy

2016 ◽  
Vol 48 ◽  
pp. e261
Author(s):  
S. Oliva ◽  
S. Cohen ◽  
F. Civitelli ◽  
M. Aloi ◽  
F. Viola ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Small Bowel ◽  
Crohn's Disease ◽  
Capsule Endoscopy ◽  
Mucosal Healing ◽  
Colon Capsule Endoscopy ◽  
Colon Capsule

Detection of Small Bowel Mucosal Healing and Deep Remission in Patients With Known Small Bowel Crohn’s Disease Using Biomarkers, Capsule Endoscopy, and Imaging

2015 ◽  
Vol 110 (9) ◽  
pp. 1316-1323 ◽  
Author(s):  
Uri Kopylov ◽  
Doron Yablecovitch ◽  
Adi Lahat ◽  
Sandra Neuman ◽  
Nina Levhar ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Small Bowel ◽  
Crohn's Disease ◽  
Capsule Endoscopy ◽  
Mucosal Healing
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