Hormonal contraception and the risk of HIV acquisition among women in South Africa

AIDS ◽  
2012 ◽  
Vol 26 (4) ◽  
pp. 497-504 ◽  
Author(s):  
Charles S. Morrison ◽  
Stephanie Skoler-Karpoff ◽  
Cynthia Kwok ◽  
Pai-Lien Chen ◽  
Janneke van de Wijgert ◽  
...  
Keyword(s):  
South Africa ◽  
Hormonal Contraception ◽  
Hiv Acquisition ◽  
Risk Of Hiv Acquisition

scholarly journals Hormonal contraception and HIV acquisition among women: an updated systematic review

2020 ◽  
Vol 46 (1) ◽  
pp. 8-16 ◽  
Author(s):  
Kathryn M Curtis ◽  
Philip C Hannaford ◽  
Maria Isabel Rodriguez ◽  
Tsungai Chipato ◽  
Petrus S Steyn ◽  
...  
Keyword(s):  
Systematic Review ◽  
Observational Study ◽  
Oral Contraceptives ◽  
Hiv Risk ◽  
Contraceptive Method ◽  
Hormonal Contraception ◽  
Hormonal Contraceptive ◽  
Contraception Use ◽  
Hiv Acquisition ◽  
Risk Of Hiv Acquisition

ObjectiveTo update a 2016 systematic review on hormonal contraception use and HIV acquisition.MethodsWe searched Pubmed and Embase between 15 January 2016 and 26 June 2019 for longitudinal studies comparing incident HIV infection among women using a hormonal contraceptive method and either non-users or users of another specific hormonal contraceptive method. We extracted information from newly identified studies, assessed study quality, and updated forest plots and meta-analyses.ResultsIn addition to 31 previously included studies, five more were identified; three provided higher quality evidence. A randomised clinical trial (RCT) found no statistically significant differences in HIV risk among users of intramuscular depot medroxyprogesterone acetate (DMPA-IM), levonorgestrel implant (LNG implant) or the copper intrauterine device (Cu-IUD). An observational study found no statistically significant differences in HIV risk among women using DMPA, norethisterone enanthate (NET-EN), implants (type not specified) or Cu-IUD. Updated results from a previously included observational study continued to find a statistically significant increased HIV risk with oral contraceptives and DMPA compared with no contraceptive use, and found no association between LNG implant and HIV risk.ConclusionsHigh-quality RCT data comparing use of DMPA, LNG implant and Cu-IUD does not support previous concerns from observational studies that DMPA-IM use increases the risk of HIV acquisition. Use of other hormonal contraceptive methods (oral contraceptives, NET-EN and implants) is not associated with an increased risk of HIV acquisition.

Response to Morrison et al., ‘Hormonal contraception and the risk of HIV acquisition’

AIDS ◽  
2007 ◽  
Vol 21 (7) ◽  
pp. 887
Author(s):  
Elizabeth G Raymond ◽  
Thomas Moench ◽  
Paul Feldblum ◽  
David Hubacher
Keyword(s):  
Hormonal Contraception ◽  
Hiv Acquisition ◽  
Risk Of Hiv Acquisition

scholarly journals Sexual partnership age pairings and risk of HIV acquisition in rural South Africa

AIDS ◽  
2017 ◽  
Vol 31 (12) ◽  
pp. 1755-1764 ◽  
Author(s):  
Adam Akullian ◽  
Anna Bershteyn ◽  
Daniel Klein ◽  
Alain Vandormael ◽  
Till Bärnighausen ◽  
...  
Keyword(s):  
South Africa ◽  
Sexual Partnership ◽  
Rural South ◽  
Hiv Acquisition ◽  
Risk Of Hiv Acquisition ◽  
Rural South Africa

scholarly journals Hormonal Contraception and the Risk of HIV Acquisition: An Individual Participant Data Meta-analysis

PLoS Medicine ◽  
2015 ◽  
Vol 12 (1) ◽  
pp. e1001778 ◽  
Author(s):  
Charles S. Morrison ◽  
Pai-Lien Chen ◽  
Cynthia Kwok ◽  
Jared M. Baeten ◽  
Joelle Brown ◽  
...  
Keyword(s):  
Meta Analysis ◽  
Hormonal Contraception ◽  
Individual Participant Data ◽  
Individual Participant ◽  
Hiv Acquisition ◽  
Risk Of Hiv Acquisition

scholarly journals Older Adults Vastly Overestimate Both HIV Acquisition Risk and HIV Prevalence in Rural South Africa

2021 ◽  
Author(s):  
Eva van Empel ◽  
Rebecca A. de Vlieg ◽  
Livia Montana ◽  
F. Xavier Gómez-Olivé ◽  
Kathleen Kahn ◽  
...  
Keyword(s):  
South Africa ◽  
Perceived Risk ◽  
Hiv Prevalence ◽  
Sub Saharan Africa ◽  
Baseline Survey ◽  
Home Based ◽  
Estimated Risk ◽  
Sub Saharan ◽  
Hiv Acquisition ◽  
Risk Of Hiv Acquisition

AbstractPerceptions of HIV acquisition risk and prevalence shape sexual behavior in sub-Saharan Africa (SSA). We used data from the Health and Aging in Africa: A Longitudinal Study of an INDEPTH Community in South Africa baseline survey. Data were collected through home-based interviews of 5059 people ≥ 40 years old. We elicited information on perceived risk of HIV acquisition and HIV prevalence among adults  ≥ 15 and ≥ 50 years old. We first describe these perceptions in key subgroups and then compared them to actual estimates for this cohort. We then evaluated the relationship between sociodemographic characteristics and accurate perceptions of prevalence in regression models. Finally, we explored differences in behavioral characteristics among those who overestimated risk compared to those who underestimated or accurately estimated risk. Compared to the actual HIV acquisition risk of < 1%, respondents vastly overestimated this risk: 35% (95% CI: 32–37) and 34% (95% CI: 32–36) for men and women, respectively. Respondents overestimated HIV prevalence at 53% (95% CI: 52–53) for those ≥ 15 years old and 48% (95% CI: 48–49) for those ≥ 50 years old. True values were less than half of these estimates. There were few significant associations between demographic characteristics and accuracy. Finally, high overestimators of HIV prevalence tested themselves less for HIV compared to mild overestimators and accurate reporters. More than 30 years into the HIV epidemic, older people in a community with hyperendemic HIV in SSA vastly overestimate both HIV acquisition risk and prevalence. These misperceptions may lead to fatalism and reduced motivation for prevention efforts, possibly explaining the continued high HIV incidence in this community.

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