Undetectable Thyroglobulin in Patients With Differentiated Thyroid Carcinoma and Residual Radioiodine Uptake on a Postablation Whole-Body Scan

2011 ◽  
Vol 36 (2) ◽  
pp. 109-112 ◽  
Author(s):  
Luca Giovanella ◽  
Sergio Suriano ◽  
Luca Ceriani ◽  
Frederik Anton Verburg
2009 ◽  
Vol 53 (7) ◽  
pp. 874-879 ◽  
Author(s):  
Maria Eduarda Mello ◽  
Rodrigo C. Flamini ◽  
Rossana Corbo ◽  
Marcelo Mamede

The radioactive iodine has been used with great value as a diagnostic and therapeutic method in patients with differentiated thyroid carcinoma previously submitted to total thyroidectomy. False-positive whole-body scans may occur due to misinterpretation of the physiologic distribution of the radioisotope or lack of knowledge on the existence of other pathologies that could eventually present radioiodine uptake. Thymic uptake is an uncommon cause of false-positive whole-body scan, and the mechanism through which it occurs is not completely understood. The present paper reports five cases of patients with differentiated thyroid cancer who presented a mediastinum uptake of radioiodine in a whole-body scan during follow-up. The patients had either histological or radiological confirmation of the presence of residual thymus gland. It is very important to know about the possibility of iodine uptake by the thymus in order to avoid unnecessary treatment, such as surgery or radioiodine therapy.


2013 ◽  
Vol 74 (3) ◽  
pp. 221-230 ◽  
Author(s):  
Leckzinscka Buton ◽  
Olivier Morel ◽  
Patricia Gault ◽  
Frédéric Illouz ◽  
Patrice Rodien ◽  
...  

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