Effects of Muscle Relaxants on Mask Ventilation in Anesthetized Persons With Normal Upper Airway Anatomy

2013 ◽  
Vol 57 (1) ◽  
pp. 16
Author(s):  
Aya Ikeda ◽  
Shiroh Isono ◽  
Yumi Sato ◽  
Hisanori Yogo ◽  
Jiro Sato ◽  
...  
2012 ◽  
Vol 117 (3) ◽  
pp. 487-493 ◽  
Author(s):  
Aya Ikeda ◽  
Shiroh Isono ◽  
Yumi Sato ◽  
Hisanori Yogo ◽  
Jiro Sato ◽  
...  

Background Recent studies suggest advantages of muscle relaxants for facemask ventilation. However, direct effects of muscle relaxants on mask ventilation remain unclear because these studies did not control mechanical factors influencing ventilation. We tested a hypothesis that muscle relaxants, either rocuronium or succinylcholine, improve mask ventilation. Methods In anesthetized adult persons with normal upper airway anatomy, tidal volumes during facemask ventilation were measured while maintaining the neutral head and mandible positions and the airway pressures of a ventilator before and during muscle paralysis induced by either rocuronium (n=14) or succinylcholine (n=17). Tidal volumes of oral and nasal airway routes were separately measured with a custom-made oronasal portioning full facemask. Behavior of the oral airway was observed by an endoscope in six additional subjects receiving succinylcholine. Results Total, oral, and nasal tidal volumes did not significantly change at complete muscle paralysis with rocuronium. In contrast, succinylcholine significantly increased total tidal volumes at 60 s after its administration (mean±SD; 4.2±2.1 vs. 5.4±2.6 ml/kg, P=0.02) because of increases of ventilation through both airway routes. Abrupt tidal volume increase occurred more through oral airway route than nasal route. Dilation of the space at the isthmus of the fauces was endoscopically observed during pharyngeal fasciculation in all six subjects. Conclusions Rocuronium did not deteriorate facemask ventilation, and it was improved after succinylcholine administration in association with airway dilation during pharyngeal fasciculation. This effect continued to a lesser degree after resolution of the fasciculation.


2021 ◽  
Vol 132 ◽  
pp. 104333
Author(s):  
Jianan Zhao ◽  
Yu Feng ◽  
Geng Tian ◽  
Cassandra Taylor ◽  
N. Sarah Arden
Keyword(s):  

Author(s):  
Ahmed Zaghw ◽  
Nabil A. Shallik ◽  
Ahmed Fayed El Geziry ◽  
Amr Elhakeem

2013 ◽  
pp. 513-516
Author(s):  
M.V. Pillai ◽  
T. Lee-Chiong
Keyword(s):  

2019 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Nicholas M. Dalesio ◽  
Rajeev Wadia ◽  
Helen Harvey ◽  
Olivia Ly ◽  
Steven A. Greenberg ◽  
...  

2015 ◽  
Vol 141 (11) ◽  
pp. 1006 ◽  
Author(s):  
Eelam Adil ◽  
Hasan Al Shemari ◽  
Amy Kacprowicz ◽  
Jennifer Perez ◽  
Kara Larson ◽  
...  
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