Computer-Aided Three-Dimensional Virtual Surgical Planning in Complex Skull Base Reconstruction for Sphenoid Wing Dysplasia in Neurofibromatosis Type 1

AbstractObjective:We present a rare case of a jugular foramen meningocoele in a 48-year-old female, with neurofibromatosis type 1, presenting with positional vertigo. We also postulate possible underlying pathophysiological mechanisms.Method:We describe the imaging findings of this rare entity and review the literature on skull base meningocoeles, particularly in the context of neurofibromatosis type 1.Results:A computed tomography scan revealed smooth expansion of the jugular foramen. Magnetic resonance imaging showed a fluid filled lesion expanding the jugular foramen and communicating with cerebrospinal fluid of the cerebellomedullary cistern superiorly.Conclusion:Skull base meningocoeles are a rare entity and we believe that this is the first reported case of a meningocoele causing enlargement of the jugular foramen in a patient with neurofibromatosis type 1. The meningocoele may have resulted from a severe form of dural ectasia or from dysplastic, weakened bone at the skull base.

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Repair of Occipital Bone Defects in Neurofibromatosis Type 1 by Means of CAD/CAM Prefabricated Titanium Plates

Craniomaxillofacial Trauma & Reconstruction ◽

10.1055/s-0037-1608699 ◽

2018 ◽

Vol 11 (4) ◽

pp. 324-330

Author(s):

Reinhard E. Friedrich ◽

Pedram Emami ◽

Christian Hagel ◽

Johannes Wikner ◽

Henning Hanken

Keyword(s):

Neurofibromatosis Type 1 ◽

Computer Aided Design ◽

Neurofibromatosis Type ◽

Bone Defects ◽

Occipital Bone ◽

Skeletal Defects ◽

Computer Aided ◽

Cad Cam ◽

Skull Trauma

Certain skeletal defects may develop in neurofibromatosis type 1 (NF1), a common tumor-suppressor syndrome, such as cranial lesions confined to the lambdoid suture region. Here, we report on the repair of osseous defects of occipital bone in a NF1 patient with history of skull trauma and tumorous hemorrhage. Computer-aided design and computer-aided manufacturing (CAD/CAM)-assisted devices were applied to safely close the bone defects. The variable phenotype of NF1 in the occipital skull region is discussed and a brief review is presented on NF1-related therapies for tumors and malformations of the occipitoparietal skull region.

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Three-dimensional virtual surgical planning (3D-VSP) in orthognathic surgery: Advantages, disadvantages and pitfalls

Journal of Orthodontics ◽

10.1177/1465312520954871 ◽

2020 ◽

pp. 146531252095487

Author(s):

Chris D Donaldson ◽

Mehmet Manisali ◽

Farhad B Naini

Keyword(s):

Computer Aided Design ◽

Orthognathic Surgery ◽

Surgical Planning ◽

Three Dimensional ◽

Open Bite ◽

Anterior Open Bite ◽

Skeletal Class ◽

Virtual Surgical Planning ◽

Skeletal Class Ii ◽

Computer Aided

In this article, the advantages, disadvantages and pitfalls of three-dimensional virtual surgical planning (3D-VSP) compared to traditional two-dimensional (2D) planning methods in orthognathic surgery are discussed, alongside a standardised protocol that can be utilised. A skeletal Class II, skeletal Class III and an anterior open bite clinical case along with their 3D-VSP management are presented, highlighting modifications that can be made to computer-aided design/computer-aided manufacture (CAD/CAM) cutting guide and plate designs.

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