RAS/TP53 co-Mutation is Associated with Worse Survival after Concurrent Resection of Colorectal Liver Metastases and Extrahepatic Disease

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Heather A. Lillemoe ◽  
Guillaume Passot ◽  
Yoshikuni Kawaguchi ◽  
Mario DeBellis ◽  
Olivier Glehen ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Extrahepatic Disease

Results of R0 Resection for Colorectal Liver Metastases Associated With Extrahepatic Disease

2004 ◽  
Vol 11 (3) ◽  
pp. 274-280 ◽  
Author(s):  
Dominique Elias ◽  
Lucas Sideris ◽  
Marc Pocard ◽  
Jean-Francois Ouellet ◽  
Val�rie Boige ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Extrahepatic Disease ◽  
R0 Resection

scholarly journals Colorectal liver metastases and concomitant extrahepatic disease: is resection justified? Single center survival analysis on 84 patients

HPB ◽  
2019 ◽  
Vol 21 ◽  
pp. S581
Author(s):  
E. Panettieri ◽  
F. Ardito ◽  
A. De Rose ◽  
A. Coppola ◽  
M. Vellone ◽  
...  
Keyword(s):  
Survival Analysis ◽  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Extrahepatic Disease ◽  
Single Center

scholarly journals Liver resection is beneficial for patients with colorectal liver metastases and extrahepatic disease

2020 ◽  
Vol 8 (4) ◽  
pp. 109-109
Author(s):  
Kristina Hasselgren ◽  
Bengt Isaksson ◽  
Bjarne Ardnor ◽  
Gert Lindell ◽  
Magnus Rizell ◽  
...  
Keyword(s):  
Liver Resection ◽  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Extrahepatic Disease

Resection of Colorectal Liver Metastases with Extrahepatic Disease

2008 ◽  
Vol 25 (6) ◽  
pp. 461-466 ◽  
Author(s):  
Robbert J. de Haas ◽  
Dennis A. Wicherts ◽  
René Adam
Keyword(s):  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Extrahepatic Disease

Concomitant Extrahepatic Disease in Patients With Colorectal Liver Metastases

2011 ◽  
Vol 253 (2) ◽  
pp. 349-359 ◽  
Author(s):  
René Adam ◽  
Robbert J. de Haas ◽  
Dennis A. Wicherts ◽  
Eric Vibert ◽  
Chadi Salloum ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Extrahepatic Disease

Colorectal liver metastases with concomitant extrahepatic disease: Is there a hope of cure?

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. e15056-e15056
Author(s):  
Katsunori Imai ◽  
Carlos Castro Benitez ◽  
Marc Antoine Allard ◽  
Eric Vibert ◽  
Antonio Sa Cunha ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Extrahepatic Disease

Whole-body MRI added to gadoxetic acid-enhanced liver MRI for detection of extrahepatic disease in patients considered eligible for hepatic resection and/or local ablation of colorectal cancer liver metastases

2019 ◽  
Vol 61 (2) ◽  
pp. 156-167
Author(s):  
Kim Sivesgaard ◽  
Lars P Larsen ◽  
Michael Sørensen ◽  
Stine Kramer ◽  
Sven Schlander ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Fdg Pet ◽  
Colorectal Liver Metastases ◽  
Local Treatment ◽  
Whole Body ◽  
Extrahepatic Disease ◽  
Liver Mri ◽  
Whole Body Mri ◽  
Pet Ct ◽  
Fdg Pet Ct

Background Fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) can detect extrahepatic disease before local treatment of colorectal liver metastases. Purpose To investigate if whole-body magnetic resonance imaging (MRI) added to gadoxetic acid liver MRI could replace FDG-PET/CT for detection of extrahepatic disease in patients with colorectal liver metastases eligible for hepatic local treatment. Material and Methods This health-research-ethics-committee-approved prospective consecutive diagnostic accuracy study with written informed consent analyzed 79 cases included between 29 June 2015 and 7 February 2017. Whole-body MRI covering the thorax, abdomen, and pelvis and FDG-PET/CT including contrast-enhanced CT was performed 0–3 days before local treatment of liver metastases. Whole-body MR images were read independently by two readers. FDG-PET/CT images were read independently by two pairs of readers. Histopathology and follow-up imaging were used as reference standard. Sensitivities and specificities were calculated and compared including noninferiority analysis. Results Seventy-five malignant lesions and 419 benign lesions were confirmed. Sensitivities of both PET/CT reader pairs 1 and 2 (56.7 and 67.9%) and MRI reader 2 (63.0%) were significantly higher than that of MRI reader 1 (42.7) (P<0.04). Specificities of both PET/CT reader pairs 1 and 2 (92.5 and 92.4%) and MRI reader 1 (91.1%) were significantly higher than that of MRI reader 2 (86.3%) ( P < 0.02). Sensitivity of MRI reader 2 was non-inferior compared to PET/CT reader pair 1. Specificities of both MRI readers were non-inferior to both PET/CT reader pairs. Conclusion For detection of extrahepatic disease in patients with colorectal liver metastases, whole-body MRI was non-inferior to FDG-PET/CT for some reader combinations. However, reader-independent non-inferiority could not be demonstrated.

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