WeightedLD: The Application of Sequence Weights to Linkage Disequilibrium
Keyword(s):
Sequence-weighting methods are commonly employed to account for biases in sequence datasets. We use a weighting scheme which considers the observed distinctiveness of sequences and apply it to calculations of linkage disequilibrium. Each sequence now contributes a weighted score to linkage disequilibrium measurements of pairwise loci. We demonstrate that this reduces the effect of uneven sampling, as underrepresented groups of sequences will each contribute more individually than redundant, similar sequences.
2007 ◽
Vol 80
(2)
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pp. 353-360
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2020 ◽
Vol 9
(10)
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pp. 390-393
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2003 ◽
Vol 71
(3)
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pp. 552-552
2002 ◽
Vol 83
(6)
◽
pp. 1440-1440
Keyword(s):
2003 ◽
Vol 34
(4)
◽
pp. 405-405
Keyword(s):
2002 ◽
Vol 10
(4)
◽
pp. 391-391
Keyword(s):