This paper mainly studies on the classification of pathological voice from normal voice based on the sustained vowel /a/. Firstly, the original 18 acoustic features are extracted. Then on the basis of the extracted parameters, this paper recognizes the pathological voice using AD Tree. During the classification stage, the cross-validation of features is also as references in the process. This method is validated with a sound database provided by the Massachusetts Eye and Ear Infirmary (MEEI). After the 10 fold cross-validation, comparing with 7 other kinds of classifiers, the experimental results show that AD Tree can get the highest recognition rate of 95.2%. The method in this paper shows that all the extracted parameters are reasonable in the following recognition process and AD tree is a good recognition way in pathological voice research.