Physiological Modeling of Concentration-Effect Relationship for Nondepolarizing Neuromuscular Blocking Drugs

2020 ◽  
Author(s):  
Hikaru Hoshino ◽  
Eiko Furutani ◽  
Tomonori Sugawara ◽  
Toshihiro Takeda ◽  
Yoshiharu Sawanobori ◽  
...  
Keyword(s):  
Neuromuscular Blocking ◽  
Concentration Effect ◽  
Physiological Modeling ◽  
Neuromuscular Blocking Drugs ◽  
Effect Relationship ◽  
Nondepolarizing Neuromuscular Blocking Drugs

scholarly journals Nondepolarizing neuromuscular blocking drugs and train-of-four fade

1995 ◽  
Vol 42 (3) ◽  
pp. 213-216 ◽  
Author(s):  
Éamon P. McCoy ◽  
Fiona M. Connolly ◽  
Rajinder K. Mirakhur ◽  
Paul B. Loan ◽  
L. Douglas Paxton
Keyword(s):  
Neuromuscular Blocking ◽  
Neuromuscular Blocking Drugs ◽  
Train Of Four ◽  
Nondepolarizing Neuromuscular Blocking Drugs

scholarly journals Sugammadex: Efficacy and Practicality in the Dental Office

2018 ◽  
Vol 65 (2) ◽  
pp. 113-118 ◽  
Author(s):  
Stephen Goetz ◽  
Benjamin Pritts ◽  
Bryant Cornelius. DDS
Keyword(s):  
Case Report ◽  
Side Effects ◽  
Neuromuscular Blocking ◽  
Neuromuscular Blocking Drugs ◽  
Dental Office ◽  
Rapid Reversal ◽  
The Common ◽  
Rescue Agent ◽  
Novel Drug ◽  
Nondepolarizing Neuromuscular Blocking Drugs

Sugammadex is a novel drug capable of reversing paralysis induced by the common steroidal nondepolarizing neuromuscular blocking drugs, rocuronium and vecuronium. Reversal is complete at any depth of blockade dependent on the dose of sugammadex administered. This allows rocuronium to be used as a rescue agent in scenarios where succinylcholine is contraindicated. Sugammadex is considered a safe drug with minimal side effects compared with traditional reversal with neostigmine and glycopyrrolate. This article features a case report where succinylcholine was undesirable and rapid reversal of paralysis with sugammadex was used during general anesthesia for dentistry.

Facilitation of Rapid Endotracheal Intubations with Divided Doses of Nondepolarizing Neuromuscular Blocking Drugs

1985 ◽  
Vol 62 (4) ◽  
pp. 392-395 ◽  
Author(s):  
Mahesh P. Mehta ◽  
Won W. Choi ◽  
Samir D. Gergis ◽  
Martin D. Sokoll ◽  
Andrew J. Adoiphson
Keyword(s):  
Neuromuscular Blocking ◽  
Neuromuscular Blocking Drugs ◽  
Nondepolarizing Neuromuscular Blocking Drugs
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