Transfer Entropy between Intracranial EEG Nodes Highlights Network Dynamics that Cause and Stop Epileptic Seizures

Author(s):  
Simon Wing ◽  
Kristin M. Gunnarsdottir ◽  
Jorge Gonzalez-Martinez ◽  
Sridevi V. Sarma
2020 ◽  
Vol 30 (12) ◽  
pp. 2050072
Author(s):  
Yanli Zhang ◽  
Rendi Yang ◽  
Weidong Zhou

To identify precursors of epileptic seizures, an EEG characteristic analysis is carried out based on a roughness-length method, where fractal dimensions and intercept values are extracted to measure the structure complexity and the amplitude roughness of EEG signals in different phases. Using the significant changes of the fractal dimension and intercept in the preictal phase with respect to those in the interictal phase, a patient-specific seizure prediction algorithm is then proposed by combining with a gradient boosting classifier. The probabilistic outputs of the trained gradient boosting classifier are further processed by threshold comparison and rule-based judgment to distinguish preictal EEG from interictal EEG and to generate seizure alerts. The prediction algorithm was evaluated on 20 patients’ intracranial EEG recordings from the Freiburg EEG database, which contains the preictal periods of 65 seizures and 499[Formula: see text]h interictal EEG. Setting the seizure prediction horizon as 2[Formula: see text]min, averaged sensitivity values of 90.42% and 91.67% with averaged false prediction rates of 0.12/h and 0.10/h were achieved for seizure occurrence periods of 30 and 50[Formula: see text]min, respectively. These results demonstrate the ability of fractal dimension and intercept metrics in predicting the occurrence of seizures.


1997 ◽  
Vol 9 (4) ◽  
pp. 249-270 ◽  
Author(s):  
Jan Pieter M. Pijn ◽  
Demetrios N. Velis ◽  
Marcel J. van der Heyden ◽  
Jaap DeGoede ◽  
Cees W. M. van Veelen ◽  
...  

2000 ◽  
Vol 9 (3) ◽  
pp. 190-195
Author(s):  
Satoshi Shirao ◽  
Masami Fujii ◽  
Tatsuo Akimura ◽  
Makoto Ideguchi ◽  
Takafumi Nishizaki ◽  
...  

Cephalalgia ◽  
2019 ◽  
Vol 39 (9) ◽  
pp. 1195-1199
Author(s):  
Pedro F Viana ◽  
Harumoto Hasegawa ◽  
Josef Jarosz ◽  
Ata Siddiqui ◽  
Richard P Selway ◽  
...  

Background and objectives Ictal epileptic headache is a rare form of painful seizure, habitually consisting of migrainous or tension-type headache. We describe a case of a patient with short-lasting, severe retroorbital pain attacks caused by frontal lobe epilepsy. Case report A 25-year-old male patient presented with recurrent attacks of paroxysmal, short-lasting, excruciating left periorbital and facial pain mainly occurring from sleep. After intracranial EEG exploration and resection of a right prefrontal focal cortical dysplasia, long-term seizure and headache remission was obtained. Discussion Our case extends the clinical and neuroanatomical spectrum of ictal epileptic headache and suggests that long-term remission can be obtained by resective epilepsy surgery. It also reinforces the role of the prefrontal cortex in the pain matrix and pain generation. Conclusion Despite its rarity, ictal epileptic headache should be suspected in selected patients, particularly those with other ictal symptoms and signs, history of epileptic seizures, or neuroimaging abnormalities.


2014 ◽  
Vol 223 (13) ◽  
pp. 2933-2941 ◽  
Author(s):  
A. C. Rodrigues ◽  
B. S. Machado ◽  
G. Florence ◽  
A. P. Hamad ◽  
A. C. Sakamoto ◽  
...  

2013 ◽  
Vol 23 (3) ◽  
pp. 270-275 ◽  
Author(s):  
Heidemarie Gast ◽  
Markus Müller ◽  
Christian Rummel ◽  
Corinne Roth ◽  
Johannes Mathis ◽  
...  

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