At present, large section conductors applied in domestic ±800kV ultra-high DC power transmission line consist of 6×720mm2, 6×900mm2 and 6×1000mm2 conductors. This paper analyzes initial engineering investment and mechanical performance of 6×JL1/G2A-720/50, 6×JL1/G3A-900/40, 6×JL1/G3A-1000/45, 6×JL1/G2A-1250/70 and 6×JL1/G2A-1520/125 conductor plans, carry out economic comparison of the whole life period of these 5 conductor plans, demonstrate economic of 6×JL1/G2A-1250/70, and 6×JL1/G2A-1520/125 conductor plans in ±800kV ultra-high DC power transmission line is more advantageous when annual loss hours is too high, and the 6×JL1/G2A-1250/70 plan can save initial investment of engineering compared to the 6×JL1/G2A-1520/125 plan.