A design of dry-mixed mortar control system based on Fieldbus and PLC was introduced in this paper. A scheme of totally integrated automation, which includes S7-300 PLC, PROFIBUS-DP Fieldbus, touch panel and etc., was proposed. Firstly, control demands and process of this system were described; secondly, hardware configuration and software design were illustrated as well. By using large-scale PLC and field level network - PROFUBUS-DP, the motions of electric motor actuators or hydraulic cylinder actuators are running well, and all sections in the process flow, like hoist, well-distributed vibration, mixing, unloading, etc can all be implemented in time and in place. Though the actual running of the control system it has been proved that the fully integrated automation production of dry-mixed mortar can be thoroughly realized.