Coexisting mutations in CARD14 and NUDT15 detected in a young female with azathioprine hypersensitivity syndrome manifested as acute generalized exanthematous pustulosis

2020 ◽  
Vol 47 (4) ◽  
Author(s):  
Chih‐Yu Chen ◽  
Chien‐Ping Chiang ◽  
Hsiang‐Cheng Chen ◽  
Hong‐Wei Gao ◽  
Wei‐Ming Wang ◽  
...  
2010 ◽  
Vol 44 (10) ◽  
pp. 1681-1682 ◽  
Author(s):  
Chaker Ben Salem ◽  
Wafa Saidi ◽  
Neila Fathallah ◽  
Chedia Jeddi ◽  
Najet Ghariani ◽  
...  

2008 ◽  
Vol 15 (2) ◽  
pp. 275-277 ◽  
Author(s):  
T Ziemssen ◽  
A Bauer ◽  
M Bär

Introduction High-dose glucocorticosteroids (GC) are the treatment of choice for acute relapses in patients with multiple sclerosis as proven by several controlled clinical trials. The common adverse effects of GC are well known Case Presentation In this study, we report on the exceptional case of a young female treated with intravenous high-dose prednisolone for optic neuritis who developed acute generalized exanthematous pustulosis (AGEP). AGEP is a rare cutaneous adverse reaction induced most frequently by antimicrobial or antihypertensive drugs and viral infections. It is characterized by a febrile erythematous and pustular rash and blood granulocytosis. Conclusion In our patient, switching to dexamethasone for the next relapse was tolerated well and is an option for treatment. AGEP is a rare adverse effect of carticosteroid treatment.


2016 ◽  
Vol 10 (2) ◽  
Author(s):  
Chloé Alberto ◽  
Maria Polina Konstantinou ◽  
Catherine Martinage ◽  
Eline Casassa ◽  
Emilie Tournier ◽  
...  

2000 ◽  
Vol 62 (1) ◽  
pp. 14-17 ◽  
Author(s):  
Maiko YOKOYAMA ◽  
Tatsuro TANAKA ◽  
Yutaka NARISAWA

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